Results 11 to 20 of about 5,910,522 (194)

Molecular and Metabolic Mechanisms Underlying Selective 5-Aminolevulinic Acid-Induced Fluorescence in Gliomas

Cancers, 2021
Simple Summary 5-aminolevulinic acid (5-ALA) is a medication that produces fluorescence in certain cancers, which enables surgeons to visualize tumor margins during surgery.
Jeffrey I. Traylor, M. Pernik, Alex C Sternisha, S. McBrayer, K. Abdullah   +4 more
semanticscholar   +1 more source

The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2018
5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj   +1 more source

5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report

Gels, 2022
The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole, Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D’Amico, Domenico Tripodi, Giovanna Iezzi, Adriano Piattelli, Morena Petrini   +8 more
doaj   +1 more source

Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer.

Photodiagnosis and Photodynamic Therapy, 2022
BACKGROUND 5-aminolevulinic acid is a protoporphyrin IX precursor used for photodynamic diagnosis. We aimed to clarify the therapeutic benefits of orally administered 5-aminolevulinic acid for photodynamic diagnosis in transurethral resection for non ...
Rikiya Taoka, Yuki Matsuoka, Mari Yamasaki, Naoya Kani, Tomoko Honda, S. Harada, Yoichiro Tohi, Takuma Kato, H. Okazoe, H. Tsunemori, Nobufumi Ueda, M. Sugimoto   +11 more
semanticscholar   +1 more source

5-Aminolevulinic acid improves chicken sperm motility [PDF]

Animal Bioscience, 2021
Objective This study investigated the effects of 5-aminolevulinic acid (5-ALA) on the motility parameters, mitochondrial membrane depolarization, and ATP levels in chicken sperm. Methods The pooled semen from Barred Plymouth Rock males was used.
Shin Taniguchi, Zhendong Zhu, Mei Matsuzaki, Masaoki Tsudzuki, Teruo Maeda   +4 more
doaj   +1 more source

Association of 5-aminolevulinic acid with intraoperative hypotension in malignant glioma surgery.

Photodiagnosis and Photodynamic Therapy, 2021
BACKGROUND Use of 5-aminolevulinic acid for photodynamic malignant tumor diagnosis reportedly causes intraoperative hypotension (systolic blood pressure < 70 mmHg) during urologic surgery.
Shumpei Morisawa, Kohei Jobu, T. Ishida, K. Kawada, H. Fukuda, Y. Kawanishi, Taku Nakayama, Shinkuro Yamamoto, Naohisa Tamura, M. Takemura, Nao Kagimoto, T. Ohta, Noritaka Masahira, H. Fukuhara, S. Ogura, T. Ueba, Keiji Inoue, M. Miyamura   +17 more
semanticscholar   +1 more source

Effect of 5-aminolevulinic Acid on Mitochondrial Activity

Frontiers in Bioscience-Scholar, 2023
Background: Mitochondrial dysfunction is considered an important mechanism in the pathogenesis of various diseases. Therefore, mitochondria are currently being considered as subjects for targeted therapies, particularly, phototherapy using 5 ...
Yuliya V. Markina, Alexander M. Markin, Tatiana V. Kirichenko, Taisiya V. Tolstik, Vadim R. Cherednichenko, Diana G. Kiseleva, Alexander N. Orekhov   +6 more
doaj   +1 more source

Case Report: Lack of Response to Givosiran in a Case of ALAD Porphyria

Frontiers in Genetics, 2022
Introduction: 5-Aminolevulinic acid dehydratase (ALAD) porphyria (ADP) is an autosomal recessive disease characterized by a profound deficiency in ALAD, the second enzyme in the heme biosynthetic pathway, and acute neurovisceral attacks with abdominal ...
Erica Graff, Karl E. Anderson, Cynthia Levy, Cynthia Levy   +3 more
doaj   +1 more source

Photodynamic therapy of acne

Biomedical Photonics, 2023
Acne is one of the most common skin conditions in the world. A number of studies have shown that photodynamic therapy (PDT) is safe and effective for both inflammatory and non-inflammatory acne and can significantly improve skin conditions in this ...
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source

Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review

Diagnostics, 2020
Background: A very important aspect in the treatment of high-grade glioma is gross total resection to reduce the risk of tumor recurrence. One of the methods to facilitate this task is intraoperative fluorescence navigation.
Marek Mazurek, Bartłomiej Kulesza, Filip Stoma, Jacek Osuchowski, Sławomir Mańdziuk, Radosław Rola   +5 more
doaj   +1 more source