Results 21 to 30 of about 20,500 (163)

Pale-green phenotype of atl31atl6 double mutant leaves is caused by disruption of 5-aminolevulinic acid biosynthesis in Arabidopsis thaliana.

PLoS ONE, 2015
Arabidopsis ubiquitin ligases ATL31 and homologue ATL6 control the carbon/nitrogen nutrient and pathogen responses. A mutant with the loss-of-function of both atl31 and atl6 developed light intensity-dependent pale-green true leaves, whereas the single ...
Shugo Maekawa, Atsushi Takabayashi, Thais Huarancca Reyes, Hiroko Yamamoto, Ayumi Tanaka, Takeo Sato, Junji Yamaguchi   +6 more
doaj   +1 more source

Efficacy of fractional CO2 laser combined with 5-aminolevulinic acid photodynamic therapy on actinic keratosis in face

Pifu-xingbing zhenliaoxue zazhi, 2022
Objective To observe clinical effects and safety of fractional CO2 laser combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) on facial actine keratosis (AK).
Ming WANG, Xin TIAN, Yuan LU, Xia WANG, Ping ZHONG, Bao CHAI, Peng WANG, Chunyan HUANG, Changzheng HUANG   +8 more
doaj   +1 more source

A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid

IJU Case Reports, 2019
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer.
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto   +12 more
doaj   +1 more source

Silencing of δ‐aminolevulinic acid dehydratase via virus induced gene silencing promotes callose deposition in plant phloem

Plant Signaling & Behavior, 2022
The δ-aminolevulinic acid dehydratase (ALAD) enzyme is an intermediate in the biosynthetic pathway of tetrapyrroles. It combines two δ‐aminolevulinic acid (δ‐ALA) molecules to form the pyrrole, porphobilinogen, an important precursor for plant pigments ...
Nabil Killiny, Shelley E. Jones, Pedro Gonzalez-Blanco   +2 more
doaj   +1 more source

Influence of lead on the chlorophyll content and on initial steps of its synthesis in greening cucumber seedlings

Acta Societatis Botanicorum Poloniae, 2014
Lead uptake by young cucumber (Couches satires L.) seedlings growing in 10-4 and 10-3 M PbCl2 solution caused δ-aminolevulinic acid synthesis inhibition, reduced the activity of δ-aminolevulinic acid dehydratase and the chlorophyll centent in the ...
Marek Burzyński
doaj   +1 more source

Determination of delta aminolevulinic acid levels in urine; a sensitive indicator of lead exposure in construction workers [PDF]

Al Ameen Journal of Medical Sciences, 2020
Background: Occupational exposure is a major source for lead poisoning in adults. Lead toxicity disrupts the functions of the digestive system, nervous system, respiratory system, reproductive system, etc.
Neelam J. Patil, Pooja V. Bhatt, Sachin A. Patharkar, Alka V. Nerurkar, Pradeep N. Surve, Kapil Bhatia   +5 more
doaj  

5-Aminolevulinic acid synthase: mechanism, mutations and medicine

, 2003
5-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5'-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate).
Bottomley, S.S., Roy, I., Sarwar, M., Sawyer, L., Baxter, R.L., Shoolingin-Jordan, P., Kahari, D., Shoolingin-Jordan, P.M., Alexeev, D., Al-Daihan, S., Kahari, I.D., Wang, S.F.   +11 more
core   +1 more source

Identification of risk factors associated with oral 5-aminolevulinic acid induced adverse events in photodynamic diagnosis−transurethral resection of bladder tumor

Photodiagnosis and Photodynamic Therapy
Background: Oral 5-aminolevulinic acid for transurethral resection of bladder tumor reduces bladder cancer recurrence compared with standard white-light transurethral resection of bladder tumor.
Yu Okabe, Yuichiro Fukuhara, Wataru Matsuoka, Nobuyuki Nakamura, Hiroshi Matsuzaki, Takeshi Miyazaki, Naotaka Gunge, Kosuke Tominaga, Kazuna Tsubouchi, Masahiro Tachibana, Chizuru Nakagawa, Fumihiro Yamazaki, Nobuhiro Haga   +12 more
doaj   +1 more source

Photodynamic Therapy with Aminolevulinic Acid Enhances the Cellular Activity of Cells Cultured on Porcine Acellular Dermal Matrix Membranes Used in Periodontology

Gels, 2023
This study aims to test a photodynamic protocol based on a gel containing aminolevulinic acid followed by red-LED (ALAD-PDT) irradiation on human gingival fibroblasts (hGFs) and osteoblasts (hOBs) cultured on a porcine acellular dermal matrix membrane ...
Morena Petrini, Emira D’Amico, Tania Vanessa Pierfelice, Gitana Maria Aceto, Maryia Karaban, Pietro Felice, Adriano Piattelli, Antonio Barone, Giovanna Iezzi   +8 more
doaj   +1 more source

X-ray structure of a putative reaction intermediate of 5-aminolaevulinic acid dehydratase

, 2003
The X-ray structure of yeast 5-aminolaevulinic acid dehydratase, in which the catalytic site of the enzyme is complexed with a putative cyclic intermediate composed of both substrate moieties, has been solved at 0.16 nm (1.6 Å) resolution.
Youell, J.H., Butler, D., Cooper, J.B., Erskine, P.T., Warren, M.J., Brindley, A.A., Shoolingin-Jordan, P.M., Wood, S.P., Coates, L.   +8 more
core   +1 more source