Results 11 to 20 of about 8,541,382 (232)
Fluorescence‐based discrimination of breast cancer cells by direct exposure to 5‐aminolevulinic acid
Cancer Medicine, 2019 Protoporphyrin IX‐fluorescence measurement is a powerful in situ approach for cancer detection after oral/topical administration of 5‐aminolevulinic acid.
Midori Morita +8 more
doaj +2 more sources
Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]
Frontiers in MicrobiologyIntroduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang +11 more
doaj +2 more sources
The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]
Biuletyn Wojskowej Akademii Technicznej, 2018 5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj +4 more sources
Plant Direct, 2018 δ‐aminolevulinic acid dehydratase (ALAD) is an important enzyme in tetrapyrrole synthesis. ALAD combines two δ‐aminolevulinic acid (δ‐ALA) molecules to form the pyrrole molecule, porphobilinogen, an important precursor for plant pigments involved in ...
Nabil Killiny +4 more
doaj +2 more sources
International Journal of Nanomedicine, 2012 Jin Ju Yoo*, Chan Kim*, Chung-Wook Chung, Young-Il Jeong, Dae Hwan KangNational Research and Development Center for Hepatibiliary Disease, Pusan National University Yangsan Hospital, Gyeongnam 626-770, Korea *These authors contributed equally to this ...
Kang DH +4 more
doaj +1 more source
5-Aminolevulinic acid-mediated photodynamic therapy for bladder cancer
International Journal of Urology, 2017 Keiji Inoue
exaly +2 more sources
Natural 5-Aminolevulinic Acid: Sources, Biosynthesis, Detection and Applications
Frontiers in Bioengineering and Biotechnology, 2022 5-Aminolevulinic acid (5-ALA) is the key precursor for the biosynthesis of tetrapyrrole compounds, with wide applications in medicine, agriculture and other burgeoning fields. Because of its potential applications and disadvantages of chemical synthesis,
Meiru Jiang +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 5-Aminolevulinic acid (5-ALA) is a natural amino acid and a precursor of heme and chlorophyll. Exogenously administered 5-ALA is metabolized into protoporphyrin IX (PpIX). PpIX accumulates in cancer cells because of the low activity of ferrochelatase, an
Yoshinori Harada +4 more
semanticscholar +1 more source
Photodynamic therapy using systemic administration of 5-aminolevulinic acid and a 410-nm wavelength light-emitting diode for methicillin-resistant Staphylococcus aureus-infected ulcers in mice. [PDF]
PLoS ONE, 2014 Bacterial resistance to antibiotics has become a worldwide problem. One potential alternative for bacterial control is photodynamic therapy. 5-aminolevulinic acid is a natural precursor of the photosensitizer protoporphyrin IX. Relatively little is known
Kuniyuki Morimoto +6 more
doaj +1 more source