Results 91 to 100 of about 13,598,018 (237)

Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus

Virology Journal, 2007
Background Coronaviruses are an important cause of infectious diseases in humans, including severe acute respiratory syndrome (SARS), and have the continued potential for emergence from animal species. A major factor in the host range of a coronavirus is
Harbison Carole E, Oura Trisha J, Aronson Jed M, McElroy Lisa J, Chu Victor C, Bauman Beverley E, Whittaker Gary R   +6 more
doaj   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Comparison of Three RT-PCR Based Methods for Relative Quantification of mRNA

Food Technology and Biotechnology, 2005
Comparison of three RT-PCR based methods: semi-quantitative, competitive and real--time RT-PCR for relative quantification of mRNA is presented. Aminopeptidase N expressed on human promyeloid HL-60 cell line, at basal and activated state, served as a ...
Andreja Ambriović-Ristov, Sanja Kapitanović, Tamara Čačev, Jelka Gabrilovac, Davorka Breljak   +4 more
doaj  

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source

Tissue-specific interactions between nuclear proteins and the aminopeptidase N promoter.

, 1991
Udgivelsesdato: 1991-Sep-25Aminopeptidase N/CD13 is a metallopeptidase found in many tissues. Aminopeptidase N activity is high in the small intestinal mucosa, moderate in the liver, and low in the spleen.
Olsen, Jørgen, Norén, O, Kärnström, U, Sjöström, H, Laustsen, Lotte   +4 more
core   +1 more source

Determination of aminopeptidase activity in cheese

, 2005
Aminopeptidase activity was studied in different types of cheese. Of the cheeses analysed having a mesophilous lactic flora, Roncal was contained the most aminopeptidase activity, coinciding with the highest ripening indices found [non-protein nitrogen ...
Martí De Castro, M. A., Martín-Hernández, M. C., M. Angeles Mart� Castro, M. Carmen Mart�n-Hern�ndez   +3 more
core   +1 more source

TRIM59 Drives Bladder Cancer Progression Through E3 Ligase‐Dependent K48‐Linked Degradation of PTRF

Cancer Science, EarlyView.
Schematic model of TRIM59‐driven BLCA progression through K48‐linked ubiquitination and proteasomal degradation of PTRF, leading to AKT activation and c‐Myc upregulation. ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood ...
Junlin Gan, Xuesong Bai, Aijie Zhang, Fei Lin, Hang Tong, Tinghao Li, Ning Xu, Xinyuan Li, Zhou Yu, Hubin Yin   +9 more
wiley   +1 more source

Structural features of ZAK kinase regulation at the ribosome

The FEBS Journal, EarlyView.
ZAK kinase binds ribosomes in various states (hibernating, translating, and colliding). Widespread ribosome collisions promote ZAK autophosphorylation and activation of the ribotoxic stress response pathway. This stress signaling pathway mediates downstream cell fate decisions such as cell cycle arrest and apoptosis. ZAKα is a MAP3K that interacts with
Shuangshuang Niu, Vienna L. Huso, Roland Beckmann, Rachel Green   +3 more
wiley   +1 more source

Biosynthesis of intestinal microvillar proteins. The effect of swainsonine on post-translational processing of aminopeptidase N

, 1983
Udgivelsesdato: 1983-Nov-15The post-translational processing of pig small-intestinal aminopeptidase N (EC 3.4.11.2) was studied in organ-cultured mucosal explants. Exposure of the explants to swainsonine, an inhibitor of Golgi mannosidase II, resulted in
Dorling, P R, Danielsen, E M, Cowell, G M, Norén, Ove, Sjöström, H   +4 more
core   +1 more source