Results 81 to 90 of about 27,424 (235)

Anti-tumor targeted drug delivery systems mediated by aminopeptidase N/CD13

Acta Pharmaceutica Sinica B, 2011
Aminopeptidase N (APN)/CD13 is a transmembrane glycoprotein, which is overexpressed on tumor neovascular endothelial cells and most tumor cells, where it plays an important role in tumor angiogenesis.
Xun Wang, Bin Wang, Qiang Zhang
doaj   +1 more source

Aminopeptidase N as a target for oral vaccine delivery

, 2010
Aminopeptidase N as a target for oral vaccine ...
Remon, Jean Paul, Melkebeek, Vesna, Vervaet, Chris, Cox, Eric, Vandamme, Katrien   +4 more
core  

Novel Potent Nonpeptide Aminopeptidase N Inhibitors with a Cyclic Imide Skeleton

, 2016
Novel Potent Nonpeptide Aminopeptidase N Inhibitors with a Cyclic Imide ...
Hiroyuki Miyachi (360087), Fuminori Kato (403146), Yuichi Hashimoto (1665289), Masanari Kato (3021183)   +3 more
core   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Aminopeptidase N is a receptor for hedgehog merbecoviruses

ABSTRACT Merbecoviruses, closely related to the highly pathogenetic Middle East Respiratory Syndrome Coronavirus (MERS-CoV), circulate in hedgehogs throughout Europe and Asia, raising concerns about zoonotic transmission to humans and domestic animals. Unfortunately, how these viruses enter host cells remains unknown,
Jin, Min, Jefferson, Victoria A., Zhao, Zhe, Catanzaro, Nicholas J., De Sabato, Luca, Keller, Emma L., Menasche, Bridget L., Hoffman, Cameron, Castelli, Anna, Di Bartolo, Ilaria, Vaccari, Gabriele, Starr, Tyler N., Seifert, Stephanie N., Castellanos, Adrian A., Han, Barbara A., Serebryannyy, Leonid, Spaulding, Alicen B., Douek, Daniel C., Moreno, Ana, Baric, Ralph S., Wilen, Craig B., Rini, James M., Letko, Michael   +22 more
openaire   +2 more sources

Inhibition of aminopeptidase N by two synthetic tripeptides

, 1996
MR-387A1 (AHPA-Val-Pro) and A2 (AHPA-Val-Hyp) were prepared as aminopeptidase N inhibitors through the synthesis of peptide MR-387A and B analogues which contained 3-amino-2-hydroxy-4-phenyl butanoic acid (AHPA) as a zinc-chelating moiety.
Choong Hwan Lee, Yung Hee Kho, Myung Chul Chung, Su-Il Kim, Ho Jae Lee, Hyo Kon Chun   +5 more
core  

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

A Novel Function for the Streptococcus pneumoniae Aminopeptidase N: Inhibition of T Cell Effector Function through Regulation of TCR Signaling

Frontiers in Immunology, 2017
Streptococcus pneumoniae (Spn) causes a variety of disease states including fatal bacterial pneumonia. Our previous finding that introduction of Spn into an animal with ongoing influenza virus infection resulted in a CD8+ T cell population with reduced ...
Lance K. Blevins, Derek Parsonage, Melissa B. Oliver, Elizabeth Domzalski, W. Edward Swords, Martha A. Alexander-Miller   +5 more
doaj   +1 more source

Transcytosis of Aminopeptidase N in caco-2 cells is mediated by a Non-cytoplasmic Signal

, 1995
In Caco-2 cells, aminopeptidase N is transported to the apical membrane from the trans Golgi network by both the direct and the indirect pathway (Matter, K., Brauchbar, M., Bucher, K., and Hauri, H.-P. (1990) Cell 60, 429-437).
Vogel, L K, Norén, Ove, Sjöström, H
core  

Probiotic Stability and Antihypertensive Activity of Peptides in Aguamiel Syrup‐Fortified Milk Protein Fermented by Lacticasebacillus rhamnosus GG

eFood, Volume 7, Issue 4, August 2026.
This study evaluates the impact of aguamiel syrup on a synbiotic fermented dairy product, focusing on antihypertensive peptide release and Lacticaseibacillus rhamnosus GG survival. While metabolic parameters remained unchanged, aguamiel syrup enhanced bioactive peptide production and antihypertensive activity (45.3%), suggesting its potential as a ...
Olvera‐Rosales Laura Berenice, Leonel‐Enríquez Jorge Eduardo, Pérez‐Escalante Emmanuel, Castañeda‐Ovando Araceli, Contreras‐López Elizabeth, Cruz‐Guerrero Alma Elizabeth, González‐Olivares Luis Guillermo   +6 more
wiley   +1 more source