Results 81 to 90 of about 13,598,018 (237)

Knockout of aminopeptidase N3 confers resistance to low concentrations of Bacillus thuringiensis Cry4Ba protoxin in Aedes aegypti

Parasites & Vectors
Background Bacillus thuringiensis is widely employed for biological control. It can effectively suppress populations of various mosquito species, including Aedes aegypti.
Xiaozhen Yang, Wanting Huang, Jiajia Wei, Xiaoxuan Xu, Jackson Champer, Lingling Zhang, Junxiang Wang   +6 more
doaj   +1 more source

Amino-benzosuberone: A novel warhead for selective inhibition of human aminopeptidase-N/CD13

, 2011
International audienceThis paper describes the design and synthesis of compounds belonging to a novel class of highly selective mammalian CD13 inhibitors.
Salomon, Emmanuel, Orsini, Alban, Alban Orsini, Patrick Pale, Defoin, Albert, Jean-Marc Weibel, Albert Defoin, Céline Tarnus, Weibel, Jean-Marc, Pale, Patrick, Mira Al-Lakkis-Wehbe, Albrecht, Sebastien, Al Lakkis-Wehbe, Mira, Sébastien Albrecht, Tarnus, Celine, Emmanuel Salomon   +15 more
core   +1 more source

Goose herbivory alters soil microbial community functional potential in a sub‐Arctic wetland

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Herbivory alters below‐ground resource dynamics via direct and indirect mechanisms, yet its effects on microbial functional potential remain poorly understood. This limits our understanding of the mechanisms that link animal, plant and microbial functional roles in ...
Jaron Adkins, Bonnie G. Waring, Karen H. Beard, Ryan T. Choi, Taylor Saunders, Emily A. Chavez, Lindsay R. Miller, Edd Hammill, Trisha B. Atwood   +8 more
wiley   +1 more source

Biliary aminopeptidase-N and the cholesterol crystallisation defect in cholelithiasis

, 1995
Several biliary proteins have cholesterol crystallisation promoting activity. One of these glycoproteins is aminopeptidase-N, a canalicular ectoenzyme. This study attempted to localise aminopeptidase-N along the biliary tree, to assess its concentration ...
Mingrone, Geltrude
core  

Plant invasion in mountain ecosystems reduces soil micro‐food web complexity at higher elevations

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Anthropogenic activities have accelerated plant invasions in mountain ecosystems, impacting the structure and functions of native plant communities. Changes in above‐ground vegetation can drive shifts in below‐ground biota, yet the effects of plant invasions on soil ...
Runjie Jiao, Yunjian Xu, Xiao Xu, Yi Wang, Jihua Wu, Xiaoli Cheng, Rongzhen Liu, Bo Li, Yupeng Geng   +8 more
wiley   +1 more source

Anti-tumor targeted drug delivery systems mediated by aminopeptidase N/CD13

Acta Pharmaceutica Sinica B, 2011
Aminopeptidase N (APN)/CD13 is a transmembrane glycoprotein, which is overexpressed on tumor neovascular endothelial cells and most tumor cells, where it plays an important role in tumor angiogenesis.
Xun Wang, Bin Wang, Qiang Zhang
doaj   +1 more source

Aminopeptidase N as a target for oral vaccine delivery

, 2010
Aminopeptidase N as a target for oral vaccine ...
Remon, Jean Paul, Melkebeek, Vesna, Vervaet, Chris, Cox, Eric, Vandamme, Katrien   +4 more
core  

Monospecific cover crops perpetuate soil biotic homogenization in croplands across diverse soils

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Croplands are known to support significant soil biotic homogenization. Cover crops are commonly used as a sustainable agriculture practice; however, many times these cover crops are composed of single‐species.
Sibo Shi, Teng Yang, Xin Gong, Saisai Cheng, Xiaoyun Chen, Xianping Li, Manuel Delgado‐Baquerizo, Linchuan Fang, Manqiang Liu   +8 more
wiley   +1 more source

A Novel Function for the Streptococcus pneumoniae Aminopeptidase N: Inhibition of T Cell Effector Function through Regulation of TCR Signaling

Frontiers in Immunology, 2017
Streptococcus pneumoniae (Spn) causes a variety of disease states including fatal bacterial pneumonia. Our previous finding that introduction of Spn into an animal with ongoing influenza virus infection resulted in a CD8+ T cell population with reduced ...
Lance K. Blevins, Derek Parsonage, Melissa B. Oliver, Elizabeth Domzalski, W. Edward Swords, Martha A. Alexander-Miller   +5 more
doaj   +1 more source

Saline versus alkaline stresses in paddy soils drive divergent microbial nutrient limitations despite shared carbon constraints

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Soil salinization and alkalization often suppress microbial functional activity, triggering negative feedback loops in microbial metabolism, degrading nutrients and agricultural productivity.
Yuqi Chen, Lingying Xu, Xu Zhao
wiley   +1 more source