Results 71 to 80 of about 13,598,018 (237)

Effects of Composite Reclamation Models of Sea Buckthorn, A Pioneer Species in Semi‐Arid Regions, on Soil Quality and Microbial Communities

Land Degradation &Development, EarlyView.
ABSTRACT Open‐pit coal mining severely degrades soil and ecosystem functions, constraining regional sustainability. Vegetation‐based reclamation has therefore been widely adopted as an effective approach to promote soil recovery and ecosystem restoration.
Bo Wen, Yun Li, Haixin Yang, Pengjie Guo, Donggang Guo, Yu Lin, Xianyun Zheng, Quanxi Zhang   +7 more
wiley   +1 more source

Tumor-derived aminopeptidase N promotes early stages of brain metastatic colonization

Cell Reports
Summary: Metastasis is a highly inefficient process, with the vast majority of disseminated cancer cells failing to form secondary tumors. To establish brain metastases, cancer cells must traverse the blood-brain barrier and rapidly adapt to the ...
Leire Bejarano, Alberto Hernández-Barranco, Vincent Roh, Rui Santalla Méndez, Eleni Lamprou, Catia F. Costa, Michelle Ballabio, Monika E. Hegi, Nadine Fournier, Johanna A. Joyce   +9 more
doaj   +1 more source

Crystal structure of X‐prolyl aminopeptidase fromCaenorhabditis elegans: A cytosolic enzyme with a di‐nuclear active site

FEBS Open Bio, 2015
Eukaryotic aminopeptidase P1 (APP1), also known as X‐prolyl aminopeptidase (XPNPEP1) in human tissues, is a cytosolic exopeptidase that preferentially removes amino acids from the N‐terminus of peptides possessing a penultimate N‐terminal proline residue.
Shalini Iyer, Penelope J. La-Borde, Karl A.P. Payne, Mark R. Parsons, Anthony J. Turner, R. Elwyn Isaac, K. Ravi Acharya   +6 more
doaj   +1 more source

Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer

BMC Cancer, 2008
Background Radiotherapy can be used to treat all stages of cervical cancer. For improving local control via radiotherapy, it is important to use additional antitumor agents.
Nawa Akihiro, Terauchi Mikio, Kajiyama Hiroaki, Shibata Kiyosumi, Tsukamoto Hirohisa, Kikkawa Fumitaka   +5 more
doaj   +1 more source

Storage treatment and diluent cause inconsistencies in commonly used fluorometric microplate enzyme assays conducted with saltmarsh soils

Limnology and Oceanography: Methods, EarlyView.
Abstract Fluorometric enzyme assays are a tool for determining potential enzyme activity in soils. A wide array of methodological approaches is adopted by different studies, making comparisons difficult. An important consideration is whether assay conditions replicate the environment of the samples or optimize potential enzyme activity.
Catrina Gore, Stefanie Nolte, Laura Lehtovirta‐Morley, Julian Mittmann‐Goesele, Peter Mueller   +4 more
wiley   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

Comparative Analysis of CrylAc Toxin Oligomerization and Pore Formation Between Bt-Susceptible and Bt-Resistant Helicoverpa armigera Larvae

Journal of Integrative Agriculture, 2012
With the long-term use of Bacillus thuringiensis (Bt) insecticide and expansion of Cry1A-expressing transgenic plants, some insect pests have developed resistance to Bt in open fields, greenhouses, and in the laboratory.
Yi-ping LI, Jun-xiang WU, Chen-xi LIU, Xiang-qun YUAN, Kong-ming WU, Ge-mei LIANG, Yu-yuan GUO   +6 more
doaj   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

Biosynthesis of intestinal microvillar proteins. Pulse-chase labelling studies on aminopeptidase N and sucrase-isomaltase

, 1982
Udgivelsesdato: 1982-Jun-15The biogenesis of two microvillar enzymes, aminopeptidase N (EC 3.4.11.2) and sucrase (EC 3.2.1.48)-isomaltase (EC 3.2.1.10), was studied by pulse-chase labelling of pig small-intestinal explants kept in organ culture.
Danielsen, Erik Michael
core   +1 more source

Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA

, 1988
The complete primary structure (967 amino acids) of an intestinal human aminopeptidase N (EC 3.4.11.2) was deduced from the sequence of a cDNA clone. Aminopeptidase N is anchored to the microvillar membrane via an uncleaved signal for membrane insertion.
Hunziker, W., Engberg, J., Gillian M. Cowell, Hans Sjöström, Kønigshøfer, E, Liselotte Laustsen, Cowell, G. M., Moller, J., Welinder, K. G., Olsen, J., Møller, Jette, Jette Møller, Jan Engberg, Laustsen, L., Danielsen, E M, Karen G. Welinder, Engberg, J, Welinder, K G, Walter Hunziker, Olsen, Jørgen, Konigshofer, E., Jørgen Olsen, Cowell, G M, Martin Spiesst, Danielsen, E. M., Ove Norén, Hansen, O C, Spiess, Martin, Noren, O., Elaine Kønigshøfer, Ole C. Hansen, Hansen, O. C., E.Michael Danielsen, Hunziker, W, Sjostrom, H., Laustsen, Lotte   +35 more
core   +2 more sources