Results 11 to 20 of about 13,225 (225)

Using microbial metalo-aminopeptidases as targets in human infectious diseases

Microbial Cell, 2021
Several microbial metalo-aminopeptidases are emerging as novel targets for the treatment of human infectious diseases. Some of them are well validated as targets and some are not; some are essential enzymes and others are important for virulence and ...
Jorge González-Bacerio, Maikel Izquierdo, Mirtha Elisa Aguado, Ana C. Varela, Maikel González-Matos, Maday Alonso del Rivero   +5 more
doaj   +1 more source

Influence of bioremediation stimulators in soil on development of oat seedlings (Avena sativa) and their aminopeptidase activity / Wpływ pozostałości substancji ropopochodnych w glebie na rozwój owsa i aktywność aminopeptydazową

Archives of Environmental Protection, 2015
Dobór technik bioremediacji jest bardzo ważny w oczyszczaniu gleby skażonej substancjami ropopochodnymi, która ma być wykorzystywanej rolniczo. Prezentowane wyniki wskazują, że na rozwój siewek owsa większy wpływ ma stosowana metoda bioremediacji niż ...
Pawełczak Małgorzata, Dawidowska-Marynowicz Barbara, Oszywa Bartosz, Koszałkowska Magdalena, Kręcidło Łukasz, Krzyśko-Łupicka Teresa   +5 more
doaj   +1 more source

Endoplasmic reticulum and its role in tumor immunity [PDF]

Frontiers in Oncology, 2015
Published onlineJournal ArticleN/
Paul eEggleton, Edwin eBremer, Marek eMichalak   +2 more
doaj   +5 more sources

Co-Catalytic Metallopeptidases as Pharmaceutical Targets [PDF]

, 2003
Understanding the reaction mechanism of co-catalytic metallopeptidases provides a starting point for the design and synthesis of new molecules that can be screened as potential pharmaceuticals. Many of the enzymes that contain co-catalytic metallo-active
Bzymek, Krzysztof P., Holz, Richard C., Swierczek, Sabina I.   +2 more
core   +2 more sources

Genetic characterization of the peptidases of Polistes versicolor (Hymenoptera: Vespidae) [PDF]

Brazilian Journal of Biology, 2003
Starch gel electrophoresis with L-leucyl-beta-naphthylamide as substrate revealed five aminopeptidases in extracts of Polistes versicolor. These enzymes are presumably products of five structural gene loci.
M. A. Del Lama, K. M. Ferreira
doaj   +1 more source

Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]

, 2003
A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Basten, E.J.W., Dekker, P.J.T., Schaap, P.J.   +2 more
core   +2 more sources

Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families

Marine Drugs, 2023
Proteolytic enzymes, also known as peptidases, are critical in all living organisms. Peptidases control the cleavage, activation, turnover, and synthesis of proteins and regulate many biochemical and physiological processes.
Isel Pascual Alonso, Fabiola Almeida García, Mario Ernesto Valdés Tresanco, Yarini Arrebola Sánchez, Daniel Ojeda del Sol, Belinda Sánchez Ramírez, Isabelle Florent, Marjorie Schmitt, Francesc Xavier Avilés   +8 more
doaj   +1 more source

Ankylosing Spondylitis: a trade Off of HLA-B27, ERAP, and pathogen interconnections? Focus on Sardinia [PDF]

, 2019
The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies.
Cauli, A, Fiorillo, Mt, Mathieu, A, Paladini, F, Sorrentino, R., Tedeschi, V   +5 more
core   +2 more sources

Arginine specific aminopeptidase from Lactobacillus brevis

Brazilian Archives of Biology and Technology, 2010
The proteolytic system of lactic acid bacteria contribute to the development of flavor during the ripening of cheese through the generation of short peptides and free amino acids, which directly or indirectly act as flavor precursors.
Arya Nandan, Amit Gaurav, Ashok Pandey, Kesavan Madhavan Nampoothiri   +3 more
doaj   +1 more source

An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes [PDF]

, 2018
The Endoplasmatic Reticulum Aminopeptidases ERAP1 and ERAP2 are implicated in a variety of immune and non-immune functions. Most studies however have focused on their role in shaping the HLA class I peptidome by trimming peptides to the optimal size ...
Cauli, A, Fiorillo, Mt, Mathieu, A, Paladini, F, Piga, M, Sorrentino, R, Tedeschi, V, Vitulano, C   +7 more
core   +2 more sources