Results 21 to 30 of about 8,494 (234)
Hypertension, 2008 Several decades of investigation have provided unequivocal support for the existence of an intrinsic brain renin-angiotensin (Ang) system (RAS) and its involvement in the control of cardiovascular functions.1,2 Essential components of the RAS, ie, renin, angiotensinogen, Ang-converting enzyme, Ang-converting enzyme 2, type 1 Ang II, and type 2 Ang II ...
Anderson J. Ferreira, Mohan K. Raizada
openaire +1 more source
Arginine specific aminopeptidase from Lactobacillus brevis
Brazilian Archives of Biology and Technology, 2010 The proteolytic system of lactic acid bacteria contribute to the development of flavor during the ripening of cheese through the generation of short peptides and free amino acids, which directly or indirectly act as flavor precursors.
Arya Nandan +3 more
doaj +1 more source
Aminopeptidases of Bacillus subtilis [PDF]
, 1975 The production of aminopeptidases, intracellularly or extracellularly, by many bacterial species has been noted (4, 5, 28). In the genus Bacillus, Aubert and Millet (2) reported an aminopeptidase in cells of _B.
Desmond, Edward Paul
core +2 more sources
Frontiers in Cellular and Infection Microbiology, 2023 We have previously demonstrated that deletion of an intracellular leucine aminopeptidase results in attenuated virulence of S. aureus. Herein we explore the role of 10 other aminopeptidases in S. aureus pathogenesis. Using a human blood survival assay we
Nathanial J. Torres +7 more
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Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases. [PDF]
, 2021 During malarial infection, Plasmodium parasites digest human hemoglobin to obtain free amino acids for protein production and maintenance of osmotic pressure.
Malcolm, TR +6 more
core +1 more source
Frontiers in Endocrinology, 2018 Thyroid disorders affect the hypothalamic-pituitary-adrenal axis with important consequences on the cardiovascular function in which the renin-angiotensin system plays a major role.
Ana B. Segarra +5 more
doaj +1 more source
Novel selective inhibitors of aminopeptidases that generate antigenic peptides [PDF]
, 2013 Endoplasmic reticulum aminopeptidases, ERAP1 and ERAP2, as well as Insulin regulated aminopeptidase (IRAP) play key roles in antigen processing, and have recently emerged as biologically important targets for manipulation of antigen presentation.
Papakyriakou, Athanasios +5 more
core +1 more source
Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Angewandte Chemie, EarlyView.Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Characterization of aminopeptidase encoding gene anp-1 and its association with development in Caenorhabditis elegans [PDF]
PeerJ, 2019 Background Aminopeptidases play important roles in various biological processes in nematodes including growth, development and reproduction. Although the aminopeptidases have been shown to regulate reproduction in Caenorhabditis elegans (C. elegans), the
Shanchun Su +3 more
doaj +2 more sources
G3: Genes, Genomes, Genetics, 2021 Puromycin-sensitive aminopeptidases are found across phyla and are known to regulate the cell-cycle and play a protective role in neurodegenerative disease.
Dorothy Benton +10 more
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