Results 31 to 40 of about 13,225 (225)

Aminopeptidase Activities Interact Asymmetrically between Brain, Plasma and Systolic Blood Pressure in Hypertensive Rats Unilaterally Depleted of Dopamine

Biomedicines, 2022
Brain dopamine, in relation to the limbic system, is involved in cognition and emotion. These functions are asymmetrically processed. Hypertension not only alters such functions but also their asymmetric brain pattern as well as their bilateral pattern ...
Inmaculada Banegas, Isabel Prieto, Ana Belén Segarra, Francisco Vives, Magdalena Martínez-Cañamero, Raquel Durán, Juan de Dios Luna, Germán Domínguez-Vías, Manuel Ramírez-Sánchez   +8 more
doaj   +1 more source

Structurally Distinct Active Sites in the Copper(II)-Substituted Aminopeptidases from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e and \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2002
The aminopeptidase from Aeromonas proteolytica (AAP) was titrated with copper, which bound sequentially at two distinct sites. Both the mono- and disubstituted forms of AAP exhibited catalytic hyperactivity relative to the native dizinc enzyme ...
Antholine, William E., Bennett, Brian, Chen, Guanjing, D\u27Souza, Ventris M., Holz, Richard C., Ustinyuk, Leila   +5 more
core   +2 more sources

Influence of Condensed and Hydrolysable Tannins on the Bacterial Community, Protein Degradation, and Fermentation Quality of Alfalfa Silage

Animals, 2022
This study evaluated the effects of hydrolysable tannin (HT) and condensed tannin (CT) on the bacterial community, fermentation quality, and proteolysis of alfalfa silage.
Wencan Ke, Huan Zhang, Shengnan Li, Yanlin Xue, Yan Wang, Wencheng Dong, Yimin Cai, Guijie Zhang   +7 more
doaj   +1 more source

Solvent and thermal stability, and pH kinetics, of proline-specific dipeptidyl peptidase IV-like enzyme from bovine serum [PDF]

, 2007
Proline-specific dipeptidyl peptidase-like (DPP IV; EC 3.4.14.5) activity in bovine serum has attracted little attention despite its ready availability and the paucity of useful proline-cleaving enzymes.
Abbott, Barry, Brendan F. O’Connor, Buckley, Bušek, Chruscinska, Ciarán Ó’Fágáin, De Meester, Deborah M. Ruth, Demuth, Dixon, Duke-Cohan, Dunn, Durinx, Edens, Engel, Fersht, FitzGerald, Gonzalez, Gorren, Grasso, Jagath, Khmelnitsky, Kikkawa, Lambeir, Lee, Maes, Mentlein, Mittal, Ogino, Ohkubo, Ohnishi, O’Cuinn, Poltorak, Poltorak, Rasmussen, Sears, Sentandreu, Sheehan, Smith, Séamus J. Buckley, Trubetskoy, Yaron, Yoshimoto   +43 more
core   +1 more source

An M29 Aminopeptidase from Listeria Monocytogenes Contributes to In Vitro Bacterial Growth but not to Intracellular Infection

Microorganisms, 2020
Aminopeptidases that catalyze the removal of N-terminal residues from polypeptides or proteins are crucial for physiological processes. Here, we explore the biological functions of an M29 family aminopeptidase II from Listeria monocytogenes (LmAmpII). We
Xian Zhang, Chiyu Guan, Yi Hang, Fengdan Liu, Jing Sun, Huifei Yu, Li Gan, Huan Zeng, Yiran Zhu, Zhongwei Chen, Houhui Song, Changyong Cheng   +11 more
doaj   +1 more source

MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae [PDF]

Open Biology, 2013
Bacterial aminopeptidases play important roles in pathogenesis by providing a source of amino acids from exogenous proteins, destroying host immunological effector peptides and executing posttranslational modification of bacterial and host proteins.
Mark W. Robinson, Kyle A. Buchtmann, Cheryl Jenkins, Jessica L. Tacchi, Benjamin B. A. Raymond, Joyce To, Piklu Roy Chowdhury, Lauren K. Woolley, Maurizio Labbate, Lynne Turnbull, Cynthia B. Whitchurch, Matthew P. Padula, Steven P. Djordjevic   +12 more
doaj   +1 more source

A comparative study of an aminopeptidase from lactic acid bacteria: a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1992
Aminopeptidase enzymes from the proteolytic systems of S.salivarius subsp.thermophilus Lactococcus lactis subsp.cremoris and Lactococcus lactis subsp.lactis have been investigated.
Midwinter, Robyn Gillian
core  

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

Advanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang, Zhong‐Yuan Yang, Shi Wang, Yan Ge, Lan Lin, Mia Madel Alfajaro, Renata B. Filler, Wan‐Yao Song, Ming‐Zhu Kong, Jin Wei   +9 more
wiley   +1 more source

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Molecules, 2018
The synthesis of racemic substituted 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one hydrochlorides was optimized to enhance reproducibility and increase the overall yield.
Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Céline Schmitt, Sarah Alavi, Isabelle Florent, Anthony Addlagatta, Efstratios Stratikos, Céline Tarnus, Sébastien Albrecht   +11 more
doaj   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source