Synthesis of MAPA Reagents and 2-Alkyl(aryl)aminopyridines from 2-Bromopyridine Using the Goldberg Reaction [PDF]
A short and economical synthesis of various 2-methylaminopyidine amides (MAPA) from 2-bromopyridine has been developed using the catalytic Goldberg reaction.
Daniel L. Comins
doaj +2 more sources
Synthesis and Fluorescent Properties of Aminopyridines and the Application in “Click and Probing” [PDF]
Unsubstituted pyridin-2-amine has a high quantum yield and is a potential scaffold for a fluorescent probe. However, the facile access to conjugated highly substituted aminopyridines and the study of their fluorescent properties is scarce. In this paper,
Zongyang Li +6 more
doaj +2 more sources
Fluorescent pyridine phosphonium salts via transmutation of metallabenzenes [PDF]
Metallabenzenes are recognized as a unique class of aromatic compounds, not only of structural and theoretical interest but also as platforms to design powerful transformations.
Yaowei Zhang +5 more
doaj +2 more sources
I2 and the Deep Eutectic Solvent ChCl–Tartaric Acid Promote the Addition–Oxidative Cyclization of 2-Aminopyridines and Chalcones to Obtain Imidazo[1,2-a]pyridines [PDF]
The synthesis of nitrogen-containing heterocycles remains a subject of significant interest due to their applications in medicinal chemistry and materials science.
Juan Lopez de Leon +5 more
doaj +2 more sources
Pharmacological management of nystagmus: An in-depth review for clinical practice [PDF]
Nystagmus, characterized by involuntary ocular movements, presents significant challenges in both congenital and acquired forms, often significantly impacting visual acuity and quality of life.
Hassan Asadigandomani +4 more
doaj +2 more sources
A NEW ROUTE FOR THE SYNTHESIS OF 2 AMINOPYRIDINES [PDF]
The 2-aminopyridines constitute a very large class of nitrogen heterocycles, which have a great biological activity, such as the antibacterial, anti-inflammatory and analgesics activity, as well as the 2-amino-4-(4-chlorophenyl)-5-oxo-5,6,7,8 ...
Zahira Kibou +5 more
doaj +1 more source
3-chloro-4-hydroxyphenylacetic acid (CHPAA) is a fungal metabolite. It is a small molecule that is useful in crystal engineering studies due to the functional groups present. Six amines were selected to form salts with CHPAA.
Remi Rolland Ngoma Tchibouanga +1 more
doaj +1 more source
Dual-State Emission of 2-(Butylamino)Cinchomeronic Dinitrile Derivatives
New representatives of 2-(butylamino)cinchomeronic dinitrile derivatives were synthesized as promising fluorophores showing dual-state emission. To characterize the influence of the length (from methyl to butyl) and the structure (both linear and ...
Konstantin V. Lipin +3 more
doaj +1 more source
In the present work, the synthesis and biological activities of substituted 2-aminopyridine δ-lactone derivatives were achieved. 4,6,6-trimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile was synthesised from 4-hydroxy-4-methylpentan-2-one, followed by ...
Fadila Salhi +3 more
doaj +1 more source
Regioselective Cobalt-Catalyzed Formation of Bicyclic 3- and 4-Aminopyridines [PDF]
Bimolecular cobalt-catalyzed [2 + 2 + 2] cycloadditions between yne−ynamides and nitriles afford bicyclic 3- or 4-aminopyridines in up to 100% yield.
Corinne Aubert (511920) +7 more
core +3 more sources

