Results 21 to 30 of about 4,314 (231)
Multicomponent, Solvent-Free Synthesis of 4-Substituted Aminopyrido[2,3-d]pyrimidines Derivatives
Chemistry Proceedings, 2023 4-substituted aminopyrido [2,3-d]pyrimidines derivatives 1a–f were synthesized via the multicomponent reaction of 2-aminopyridines, triethyl orthoformate, and diverse primary amines under solvent-free conditions.
Fatima Belhadj +4 more
doaj +1 more source
Results in Chemistry, 2023 A novel Ni-I2 catalytic system was introduced for the synthesis of 2-arylimidazo[1,2-a]pyridines from readily available arylmethyl ketones and 2-aminopyridines as the starting materials.
Rose Mary Philip +2 more
doaj +1 more source
4-Aminopyridine — A Review [PDF]
Anaesthesia and Intensive Care, 1982 4-aminopyridine is the first of the aminopyridines to be used in clinical practice. It blocks potassium channels and thereby increases acetylcholine, and possibly noradrenaline, release at nerve terminals. In man the drug has a significant action at the neuromuscular junction, but has little effect on the autonomic nervous system or muscle (smooth ...
N, Soni, P, Kam
openaire +2 more sources
Results in Chemistry, 2022 The first manganese-iodine catalyzed Ortoleva-King type protocol for the synthesis of imidazo[1,2-a]pyridines has been established. This interesting methodology involves the use of less toxic, readily available and easy to handle MnO2 and molecular ...
Thaipparambil Aneeja +2 more
doaj +1 more source
Efficient Multicomponent Catalyst-Free Synthesis of Substituted 2-Aminopyridines [PDF]
, 2020 2-aminopyridines scaffolds are an important class of nitrogen heterocyclic compounds with a wide range of biological activities. Multicomponent reactions (MCRs) are useful methods for the construction of nitrogen heterocyclic compounds.
M. Pilar Vázquez-Tato +6 more
core +1 more source
2‑Aminopyridines via Reaction of Pyridine N‑Oxides and Activated Isocyanides [PDF]
, 2016 A practical and efficient method for the synthesis of substituted 2-aminopyridines from pyridine N-oxides is reported. Yields of purified, isolated products of up to 84% are observed for the one-pot, two-step process.
Mitchell Vamos (1837279) +1 more
core +3 more sources
Journal of Saudi Chemical Society, 2018 A simple and efficient protocol has been demonstrated for the preparation of densely functionalized 3-aroylimidazo[1,2-a]pyridines from 2-aminopyridines and chalcones using RuCl3·H2O/I2 catalytic system.
P.V. Sri Ramya +5 more
doaj +1 more source
Mechanisms for the acetylation of aminopyridines [PDF]
, 1978 Rates of acetylation of aminopyridines and some ring methyl-substituted derivatives, with acetic anhydride in acetone at 36°, are reported. The results indicate that rate-determining acetylation is directly at the amino nitrogen for all 2- and 3 ...
LW Deady, DC Stillman
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Adsorption of Aminopyridines to Phosphatidylserine Vesicles [PDF]
, 1986 Intrinsic association constants were determined for a series of aminopyridines on phosphatidylserine vesicles, through determination of electrophoretic mobility.
Wright, Colin
core +2 more sources
Conversion of Aryl Azides to Aminopyridines [PDF]
, 2022 A longstanding challenge in fundamental functional group interconversion has been the direct transformation of benzene into pyridine via nitrogen insertion and carbon deletion.
Noah Z. Burns (1266771) +1 more
core +1 more source