Results 41 to 50 of about 4,314 (231)

Synthesis of [(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)amino]azines

Molecules, 2011
The reactions of 2-, 3- and 4-aminopyridines with 4,5-dichloro-1,2,3-dithiazol-ium chloride (Appel salt) 4 to give N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)pyridin-X-amines 1a (X = 2), 1g (X = 3) and 1k (X = 4) were optimized with respect to base ...
Panayiotis A. Koutentis, Maria Koyioni, Sophia S. Michaelidou   +2 more
doaj   +1 more source

Synthesis of Pyridin-1(2H)-ylacrylates and the Effects of Different Functional Groups on Their Fluorescence

Molecules, 2023
While fluorescent organic materials have many potential as well as proven applications and so have attracted significant attention, pyridine–olefin conjugates remain a less studied subset of such systems.
Weiguang Yang, Danyang Luo, Guanrong Li, Qiaoli Luo, Martin G. Banwell, Lanmei Chen   +5 more
doaj   +1 more source

General and Mild Preparation of 2-Aminopyridines [PDF]

, 2016
A general and facile one-pot amination procedure for the synthesis of 2-aminopyridines from the corresponding pyridine-N-oxides is presented as a mild alternative to SNAr chemistry. A variety of amines and heterocyclic-N-oxides participate effectively in
Sandra Jennings (2216743), Liuqing Wei (839643), Allyn T. Londregan (1463164)   +2 more
core   +1 more source

[2 + 2] Cycloaddition/Retro-Electrocyclization/Decarboxylation Reaction Sequence: Access to 4‑Aminopyridines from Methylideneisoxazolones and Ynamines [PDF]

, 2023
4-(1-Aminoallylidene)isoxazol-5-ones were synthesized in good yields by the [2 + 2]cycloaddition–retro-electrocyclization reaction of 4-methylideneisoxazol-5(4H)-ones with ynamines.
Ekaterina E. Galenko, Alexander F. Khlebnikov (1537960), Mikhail S. Novikov, Mikhail S. Novikov (1537957), Alexander F. Khlebnikov, Ekaterina E. Galenko (3093012)   +5 more
core   +1 more source

Improvement of diaphragm and limb muscle isotonic contractile performance by K⁺ channel blockade

Journal of NeuroEngineering and Rehabilitation, 2010
The K+ channel blocking aminopyridines greatly improve skeletal muscle isometric contractile performance during low to intermediate stimulation frequencies, making them potentially useful as inotropic agents for functional neuromuscular stimulation ...
Pollarine Jennifer, van Lunteren Erik
doaj   +1 more source

Simple Synthetic Approach to N-(Pyridin-2-yl)imidates from Nitrostyrenes and 2-Aminopyridines via the N-(Pyridin-2-yl)iminonitriles as Intermediates

Molecules, 2023
A facile, green, synthetic protocol of several substituted N-(pyridin-2-yl)imidates from nitrostyrenes and 2-aminopyridines via the corresponding N-(pyridin-2-yl)iminonitriles as intermediates is reported.
Andriani G. Chaidali, Ioannis N. Lykakis
doaj   +1 more source

Ruthenium Trispyrazolylborate Complexes. 18. Aminocarbene Ruthenium Complexes Derived from Terminal Alkynes and 2-Aminopyridines [PDF]

, 2016
The reactions of RuTp(COD)Cl with the bidentate ligands 2-aminopyridine (apy), 2-amino-4-picoline (apic), and 2-(methylamino)pyridine (mapy) in the presence of terminal alkynes HC⋮CR (R = Ph, n-Bu, C6H9) afford the cyclic aminocarbene complexes RuTp ...
Alexandra Hummel (3081123), Eva Rüba (2979726), Roland Schmid (253836), Kurt Mereiter (674426), Karl Kirchner (1292109)   +4 more
core   +3 more sources

Use-dependent potentiation of voltage-gated calcium channels rescues neurotransmission in nerve terminals intoxicated by botulinum neurotoxin serotype A

Scientific Reports, 2017
Botulinum neurotoxins (BoNTs) are highly potent toxins that cleave neuronal SNARE proteins required for neurotransmission, causing flaccid paralysis and death by asphyxiation.
Phillip H. Beske, Katie M. Hoffman, James B. Machamer, Margaret R. Eisen, Patrick M. McNutt   +4 more
doaj   +1 more source

Syntheses of novel pyridine-based low-molecular-weight luminogens possessing aggregation-induced emission enhancement (AIEE) properties

Beilstein Journal of Organic Chemistry, 2022
Novel pyridine-based fluorescing compounds, viz. pyrido[1,2-a]pyrrolo[3,4-d]pyrimidines 3a,b and N-methyl-4-((pyridin-2-yl)amino)maleimides 4a–e, were selectively prepared by a one-pot reaction between a functionalized maleimide and 2-aminopyridines with
Masayori Hagimori, Tatsusada Yoshida, Yasuhisa Nishimura, Yukiko Ogawa, Keitaro Tanaka   +4 more
doaj   +1 more source

One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction

Beilstein Journal of Organic Chemistry, 2016
A novel three-component reaction has been developed to assemble biologically and pharmaceutically important tetracyclic fused imidazo[1,2-a]pyridines in a one-pot fashion utilizing readily available 2-aminopyridines, isatins and isocyanides.
Bo Yang, Chuanye Tao, Taofeng Shao, Jianxian Gong, Chao Che   +4 more
doaj   +1 more source