Results 71 to 80 of about 4,314 (231)

Iron-Catalyzed Formation of 2‑Aminopyridines from Diynes and Cyanamides [PDF]

open access: yes, 2016
Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and
Janis Louie (1348188)   +2 more
core   +1 more source

Rapid protium-deuterium exchange of 4-aminopyridines in neutral D2O under microwave irradiation [PDF]

open access: yes, 2016
4-Aminopyridines undergo surprisingly rapid and highly-selective H/D exchange at C-2 and C-6 in neutral D2O upon microwave irradiation at only 190 °C for 2 h in a sealed vessel.
Hussein I Sharhan (16233875)   +2 more
core   +2 more sources

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

The aminolysis of p-nitrophenyl acetate by aminopyridines. Mechanisms in aqueous and aprotic solvents [PDF]

open access: yes, 1980
In dimethyl sulfoxide, the aminolysis of p-nitrophenyl acetate by aminopyridines results in amide formation, through nucleophilic catalysis by the ring nitrogen for 4-aminopyridine, but by direct amino nitrogen attack for 2-aminopyridine (as previously ...
LW Deady, WL Finlayson
core   +1 more source

SYNTHESIS AND PRECLINICAL STUDY OF ANTIOXIDANT ACTIVITY OF [1,2,4]TRIAZOLO[1,5-A]PYRIDINE DERIVATIVES

open access: yesBiota. Human. Technology, 2022
Purpose. Synthesis and study of antioxidant properties of [1,2,4]triazolo[1,5-a]pyridine derivatives and their potential toxicity using preclinical diagnostic methods. Methodology.
Олександр Смольський   +3 more
doaj   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad   +2 more
wiley   +1 more source

Development of membrane conductance of chick skeletal muscle in culture. II. Effect of aminopyridines [PDF]

open access: yes, 1980
The effects of 4-aminopyridine and 3,4-diaminopyridine on membrane parameters during differentiation of embryonic chick skeletal muscle in culture have been studied. Both agents caused depolarization of fibres at all stages of development.
W. F. Dryden, C. M. Thomson
core   +1 more source

Curing Behavior and Adhesion Performance of a One‐Component Epoxy Resin Based on a Dual‐Locked Thermal Latent Curing Agent

open access: yesJournal of Polymer Science, EarlyView.
In this study, curing behavior of epoxy resins using a dual‐locked thermal latent curing agent (DCA) was analyzed using DSC and FT‐NIR. The DCA was successfully dissolved in the bisphenol A type epoxy resin (DGEBA). Furthermore, the prepared one‐component epoxy resin was used as an adhesive and achieved excellent adhesive strength (> 25 MPa).
Yukai Ito, Daisuke Aoki, Koji Arimitsu
wiley   +1 more source

Microwave-Assisted Reaction of 2,3-Dichloronaphthoquinone with Aminopyridines [PDF]

open access: yes, 2009
The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all ...
Tapia, Ricardo A.   +3 more
core   +1 more source

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

open access: yesSmart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding   +8 more
wiley   +1 more source

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