Results 1 to 10 of about 20,539 (167)

Research progress on branched-chain amino acid aminotransferases

Frontiers in Genetics, 2023
Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer between branched-chain amino acids and branched-chain α-ketoacids in cells.
Chen Keping
exaly   +3 more sources

Aminotransferases disorders associated with venous thromboembolic events in patients infected with COVID-19

Annals of Hepatology, 2021
Introduction and objectives: Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of venous thromboembolic (VTE) events and elevated aminotransferases (AT).The objective of this work ...
Amer Hamade, Dominique Stephan
exaly   +3 more sources

Aminotransferases as causal factors for metabolic syndrome: A bidirectional Mendelian randomization study

PLoS ONE
BackgroundCirculating aminotransferases (ALT and AST) have been used as biomarkers for liver injury. The causal relationships between aminotransferases and metabolic syndrome remain ambiguous.MethodsWe conducted bidirectional and multivariable Mendelian ...
Meng Lingyu, Li Hongguang, Zhang Mingdong, Li Na, Liu Yahui   +4 more
exaly   +3 more sources

VIRAL HEPATITIS E IN PLEVEN REGION – CLINICAL, LABORATORY AND EPIDEMIOLOGICAL CHARACTERISTICS [PDF]

Journal of IMAB, 2021
Viral hepatitis E (VHE) is endemic in most countries nowadays. Our purpose was to analyze the characteristics of VHE in the Pleven region. Material and Methods: We performed a retrospective analysis of clinical, laboratory, and epidemiological data of ...
Galya Gancheva
doaj   +1 more source

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study

Frontiers in Medicine, 2023
BackgroundLow muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle mass.
Emily James, Emily James, Emily James, Stuart Goodall, Simon Nichols, Simon Nichols, Karen Walker, Sean Carroll, Alasdair F. O’Doherty, Lee Ingle   +9 more
doaj   +1 more source

Conversion of Racemic Unnatural Amino Acids to Optically Pure Forms by a Coupled Enzymatic Reaction

Molecules, 2021
Genetic code expansion (GCE) technology is a useful tool for the site-specific modification of proteins. An unnatural amino acid (UAA) is one of the essential components of this technique, typically required at high concentration (1 mM or higher) in ...
Hannae Lee, Dongchan Kim, Sooin Kim, Hyun Soo Lee   +3 more
doaj   +1 more source

Intermittent fasting causes metabolic stress and leucopenia in young mice [PDF]

The Ukrainian Biochemical Journal, 2019
Overweight and obesity became the worldwide epidemic resulting from overeating especially when a so-called Western diet rich in carbohydrates and fats is used.
O. M. Sorochynska, M. M. Bayliak, Y. V. Vasylyk, O. V. Kuzniak, I. Z. Drohomyretska, A. Ya. Klonovskyi, J. M. Storey, K. B. Storey, V. I. Lushchak   +8 more
doaj   +1 more source

Features of the influence of S-ethyl-4-aminobenzene thiosulfonate on some biochemical parameters of rat blood under the condition of Cr(VI) intoxication

Біологічні студії, 2023
Background. The main pathway of Cr(VI) cytotoxicity is activation of oxidative stress in cells of living organisms, resulting in an imbalance of blood biochemical para­me­ters.
B. I. Kotyk, R. Ya. Iskra, V. M. Merlavsky   +2 more
doaj   +1 more source

Evolutionary relationships among aminotransferases [PDF]

European Journal of Biochemistry, 1989
A data base was compiled containing the amino acid sequences of 12 aspartate aminotransferases and 11 other aminotransferases. A comparison of these sequences by a standard alignment method confirmed the previously reported homology of all aspartate aminotransferases and Escherichia coli tyrosine aminotransferase.
Mehta PK, Hale TI, Christen P
openaire   +3 more sources

Synthesis and Enzymatic Conversion of Amino Acids Equipped with the Silanetriol Functionality: A Prelude to Silicon Biodiversification

ChemistryEurope, 2023
Synthetic routes are reported for the three analogues of the simplest L‐2‐amino‐dicarboxylic acids, aspartate, glutamate, and aminoadipate, in which the silanetriol group (Si(OH)3) replaces the distal carboxyl group (CO2H).
Dr. Jade Dussart‐Gautheret, Dr. Julie Rivollier, Dr. Cédric Simon, Dr. Alessandro De Simone, Dr. Jérôme Berthet, Prof. Stéphanie Delbaere, Régina Maruchenko, Claire Troufflard, Dr. Denis Lesage, Dr. Yves Gimbert, Dr. Gilles Lemière, Dr. Philippe Marlière, Prof. Louis Fensterbank   +12 more
doaj   +1 more source