Results 21 to 30 of about 23,342 (303)
Lysine acetylsalicylate (LAS) is an analgesic used for the prevention of cardiovascular disease with few adverse though its effect on the hepatorenal and hematological parameters remains unclear. 45 mature male Wistar rats were equally divided into three
Ibrahim M. El-Ashmawy +4 more
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AGXT2: a promiscuous aminotransferase [PDF]
Alanine-glyoxylate aminotransferase 2 (AGXT2) is a multifunctional mitochondrial aminotransferase that was first identified in 1978. The physiological importance of AGXT2 was largely overlooked for three decades because AGXT2 is less active in glyoxylate metabolism than AGXT1, the enzyme that is deficient in primary hyperoxaluria type I.
Roman N, Rodionov +3 more
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Evolutionary origin and functional diversification of aminotransferases [PDF]
Aminotransferases (ATs) are pyridoxal 5′-phosphate–dependent enzymes that catalyze the transamination reactions between amino acid donor and keto acid acceptor substrates.
Yoshikuni, Yasuo +10 more
core +1 more source
Biological activity of humic substances in the liver of Mongolian gerbils (Meriones unguiculatus)
One important reason for non-use of medicinal drugs is their hepatotoxicity. The search for new natural biologically active substances with hepatoprotective properties and which are cost-effective is an important task today.
D. Serova, O. Taran, O. Dyomshina
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Aspartate aminotransferase/alanine aminotransferase ratio and subsequent cancer development [PDF]
AbstractBackgroundWe aimed to evaluate the association between the aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio and subsequent development of any type of cancer in an apparently healthy population.MethodsWe conducted a retrospective cohort study at St. Luke's International Hospital, Tokyo, Japan between 2005 and 2018.
Daiki Kobayashi +3 more
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Acylation of aspartate aminotransferase [PDF]
1. Acetylation of aspartate aminotransferase from pig heart inhibits completely the enzymic activity when the coenzyme is in the amino form (pyridoxamine phosphate) or when the coenzyme has been removed, but not when the coenzyme is in the aldehyde form (pyridoxal phosphate). 2.
C, Turano +3 more
openaire +2 more sources
Among pollutants a significant threat is posed by heavy metals, nitrate fertilizers and industrial waste. However, people also contribute to this threat through bad habits such as smoking and alcohol.
P. H. Lyhatskyi +3 more
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Biochemical and histological studies on the possible protective impact of the herb basil (Ocimum basilicum) on adriamycin induced toxicity in rats. I. Influence on the liver. [PDF]
The purpose of this work was to evaluate the effect of basil (Ocimum basilicum) against hepatotoxicity induced in albino rats by the anticancer drug adriamycin (ADR).
M.F.F Bayomy, S.A. Sakr, Gendia S.E. M
doaj +1 more source
The aim of our study was to examine the effectiveness of the enterosgel sorbent in the terms of simultaneous destruction of rats by karbofos and carbon tetrachloride.
L. А. Boyko +2 more
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Association between Serum Liver Enzymes and Cardiovascular Diseases: A Case-control Study among Adults with Cardiovascular Disease [PDF]
Introduction: Cardiovascular Diseases (CVDs) are the leading cause of global morbidity and mortality. However, their prevalence is disproportionately distributed, with the highest rate in low-income countries, moderate in middle-income countries, and the
Naval Kishor Yadav +5 more
doaj +1 more source

