Enhanced Antioxidant and Neuroprotective Properties of Pterostilbene (Resveratrol Derivative) in Amorphous Solid Dispersions. [PDF]
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Reply to Miller et al. Comment on "Hermeling et al. Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions. <i>Pharmaceutics</i> 2022, <i>14</i>, 2145". [PDF]
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From formulation to structure: 3D electron diffraction for the structure solution of a new indomethacin polymorph from an amorphous solid dispersion. [PDF]
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Photodissociation dynamics of amorphous solid water and amorphous solid methanol
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The physical state of a dosage form, crystalline versus amorphous, is critical in determining its solid-state physical and chemical properties. This minireview describes the physics associated with the preparation and storage of amorphous solids including a review of the common theories of the glass transition and relaxation processes.
Lori R, Hilden, Kenneth R, Morris
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Sustained-release amorphous solid dispersions
Drug Delivery and Translational Research, 2018The use of amorphous solid dispersions (ASD) to overcome poor drug solubility has gained interest in the pharmaceutical industry over the past decade. ASDs are challenging to formulate because they are thermodynamically unstable, and the dispersed drugs tend to recrystallize.
Julien, Maincent, Robert O, Williams
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Photoconduction in Amorphous Organic Solids
ChemPhysChem, 2008AbstractHerein, we focus on the principles of photoconduction in random semiconductors—the key processes being optical generation of charge carriers and their subsequent transport. This is not an overview of the current work in this area, but rather a highlight of elementary processes, their involvement in modern devices and a summary of recent ...
Dirk, Hertel, Heinz, Bässler
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Thermal conductivity of amorphous solids
Physical Review B, 1986The thermal conductivities of glassy solids, when scaled by material parameters, have a similar magnitude and temperature dependence, from the lowest temperatures yet measured, to the melt. Both empirical results and theoretical models are reviewed briefly.
, Freeman, , Anderson
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Nonlinear elasticity of amorphous solids
Physical Review Letters, 1989Structural phase transitions in amorphous solids associated with vanishing bulk modulus K or shear modulus \ensuremath{\mu} are considered. We find that the transition (realized in gels) at K=0, though of second order, does not exhibit true scaling behavior of density fluctuations.
, Golubovic, , Lubensky
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Solid State Amorphization of Pharmaceuticals
Molecular Pharmaceutics, 2008Amorphous solids are conventionally formed by supercooling liquids or by concentrating noncrystallizing solutes (spray-drying and freeze-drying). However, a lot of pharmaceutical processes may also directly convert compounds from crystal to noncrystal which may have desired or undesired consequences for their stability. The purpose of this short review
J F, Willart, M, Descamps
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