Results 101 to 110 of about 30,050 (289)

Engineering of Nanofibrous Amorphous and Crystalline Solid Dispersions for Oral Drug Delivery

open access: yesPharmaceutics, 2018
Poor aqueous solubility (<0.1 mg/mL) affects a significant number of drugs currently on the market or under development. Several formulation strategies including salt formation, particle size reduction, and solid dispersion approaches have been ...
Laura Modica de Mohac   +3 more
doaj   +1 more source

Liquid Phase Transmission Electron Microscopy: A Window into the Early Stages of Complex Material Formation

open access: yesAdvanced Functional Materials, EarlyView.
Liquid‐phase transmission electron microscopy enables direct observation of nucleation and growth processes in solution. This review is dedicated to the remembrance of Helmut Cölfen and highlights recent studies on complex materials—oxides, biominerals, organic–inorganic crystals—which were central to his research activity. It summarizes key milestones,
Charles Sidhoum   +5 more
wiley   +1 more source

Pharmaceutical technologies for improving drug loading in the formulation of solid dispersions

open access: yes, 2013
textIt is estimated that 90% of new chemical entities in development pipelines exhibit poor aqueous solubility. For compounds not limited by biological membrane permeability, this poor aqueous solubility is the limiting factor in bioavailability ...
O'Donnell, Kevin Patrick
core  

Improved Physicochemical Characteristics of Amorphous Drug Solid Dispersions [PDF]

open access: yes, 2020
In order to improve the solubility, stability and the dissolution rate of carbamazepine, amorphous carbamazepine, solid dispersion (SD) of carbamazepine with Polyacrylic acid (PAA) and co-precipitate with PAA and hydroxypropylmethyl cellulose (HPMC) in ...
B Rath, A Pandey
core  

Optoelectronic Synaptic Devices Using Molecular Telluride Phase‐Change Inks for Three‐Factor Learning

open access: yesAdvanced Functional Materials, EarlyView.
Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner   +14 more
wiley   +1 more source

Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

open access: yes, 2015
Eun-Sol Ha,1 Jeong-Soo Kim,2 In-hwan Baek,3 Jin-Wook Yoo,1 Yunjin Jung,1 Hyung Ryong Moon,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2Dong-A ST Co Ltd, Yongin, 3College of Pharmacy, Kyungsung University, Busan, South Korea Abstract:
Moon HR   +6 more
core  

Processing impact on the performance of amorphous solid dispersions

open access: yes, 2018
The level of understanding of amorphous solid dispersions has grown significantly in the last two decades. A number of commercial amorphous solid dispersions have been approved and they have become the industry norm for overcoming poor water-solubility ...
Haser, Abbe Jeanne
core   +1 more source

Synthesis of silver nano particles and fabrication of aqueous Ag inks for inkjet printing [PDF]

open access: yes, 2011
The main problem in preparing stable and printable inks containing nanoparticles for inkjetprinting is to overcome the strong agglomeration of the particles in dispersion medium.
Kosmala, A.   +7 more
core   +1 more source

Enhancement of the Solubility and Dissolution Rate of Rebamipide by Using Solid Dispersion Technique (Part I)

open access: yesIraqi Journal of Pharmaceutical Sciences, 2018
Solid dispersion is an attractive tool of pharmaceutical technology used to improve the physical properties of drugs. Among these properties is to enhance the solubility of the drugs.
Muna Y. Ismail, Mowafaq M. Ghareeb
doaj   +1 more source

Oxygen‐Tunnel Indium Tin Oxide Vertical Channel Transistors with Enhanced Current Density and Reliability for Monolithic 3D Compute‐In‐Memory Systems

open access: yesAdvanced Functional Materials, EarlyView.
Oxygen‐tunnel (OT) indium tin oxide (ITO) vertical channel transistors (VCTs) enable reliable, high‐density gain‐cell memory for monolithic 3D integration. A sandwiched SiN/SiO2/SiN OT stack selectively regulates oxygen transport, suppressing parasitic electrode oxidation while stabilizing channel oxygen vacancies, thereby suppressing carrier injection
Hyeonho Gu   +17 more
wiley   +1 more source

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