Results 101 to 110 of about 2,340,313 (291)

Preparation, characterization and evaluation of the in vivo trypanocidal activity of ursolic acid-loaded solid dispersion with poloxamer 407 and sodium caprate

Brazilian Journal of Pharmaceutical Sciences, 2015
Ursolic acid is a promising candidate for treatment of Chagas disease; however it has low aqueous solubility and intestinal absorption, which are both limiting factors for bioavailability. Among the strategies to enhance the solubility and dissolution of
Josimar Oliveira Eloy, Juliana Saraiva, Sérgio de Albuquerque, Juliana Maldonado Marchetti   +3 more
doaj   +1 more source

Atomic‐Scale Visualization of Topotactic Resistive Switching in Epitaxial La0.5Sr0.5CoOx Neuromorphic Memristors

Advanced Functional Materials, EarlyView.
Forming‐free epitaxial Pt/La0.5Sr0.5CoOx (LSCO)/La0.5Sr0.5MnO3 (LSMO) memristors exhibit heterogeneous and partially reversible topotactic switching involving brownmillerite (BM)‐, Grenier (GN)‐like‐, and perovskite (PV)‐like configurations. Atomic‐resolution scanning transmission electron microscopy and in situ transmission electron microscopy resolve
Zi‐Qin Hong, Yen‐Jung Chen, Shih‐Chao Chang, Jui‐yuan Chen, Jan‐Chi Yang, Wen‐Wei Wu   +5 more
wiley   +1 more source

A solid one-dimensional microstructured optical fiber with high nonlinearity and low dispersion at 1.55 microns

, 2009
We report on the fabrication of a solid one-dimensional microstructured fiber with high nonlinearity and low dispersion at 1.55µm. A four-wave-mixing based tunable wavelength-conversion scheme was experimentally demonstrated in just 1.5m of this ...
Camerlingo, A., Horak, P., Petropoulos, P., Parmigiani, F., Richardson, D.J., Poletti, F., Loh, W.H., Feng, X.   +7 more
core   +1 more source

Lone‐Pair‐Induced Lattice Distortion in Lead‐Free Hybrid Perovskites for High‐Performance Nanogenerators

Advanced Functional Materials, EarlyView.
A lead‐free tin‐based hybrid perovskite is designed in which stereochemically active lone‐pair electrons on tin distort the crystal lattice and break its symmetry. Blended into a flexible polymer, the material converts pressure into electricity at milliwatt‐scale power density and continues working far below freezing, powering a commercial wristwatch ...
Majid Haji Bagheri, Asif Abdullah Khan, Md Fahim Al Fattah, Mahmoud Almadhoun, Shamaila Shahzadi, Aixi Pan, Md Soyaeb Hasan, Henry Wu, Arash Aghigh, Bhawna Bhawna, François Légaré, Vivek Maheshwari, Dayan Ban   +12 more
wiley   +1 more source

ADVANCES IN SOLID DISPERSION TECHNOLOGY AND ITS APPLICATIONS IN THE DEVELOPMENT OF SOLID DOSAGE FORMS [PDF]

, 2016
Amorphous solid dispersions are extensively used as a strategy for improving the bioavailability of poorly water - soluble compounds in past decade.
Bhirud, Yogesh D, Phalak, Harshada M
core   +1 more source

Reaction‐Time pH Stabilization by Poly(acrylic acid) with Ethanol‐Mediated Growth Control for Efficient Hydrothermal Sb2(S,Se)3 Solar Cells

Advanced Functional Materials, EarlyView.
Poly(acrylic acid) acts as a reaction‐time pH buffer during hydrothermal Sb2(S,Se)3 growth through its COOH/COO‐ equilibrium. When combined with ethanol‐regulated growth, this buffering strategy reduces Sb‐O related surface disorder, improves local electronic uniformity and carrier collection, and increases the champion solar‐cell efficiency to 10.25%,
Juhee Lee, Geumha Lim, Wookyung Jeon, Seongju Park, Jinwoo Chu, Yohan Yoon, William Jo, Byungha Shin   +7 more
wiley   +1 more source

Impact of the polymer dispersity on the properties of curcumin/polyvinylpyrrolidone amorphous solid dispersions

International Journal of Pharmaceutics
Amorphous solid dispersions (ASD) are known to enhance the absorption of poorly water-soluble drugs. In this work we synthesise well-defined Polyvinylpyrrolidone (PVP) to establish the impact of dispersity and chain-end functionality on the physical properties of Curcumin (CUR)/PVP ASD.
Samsoen, Simon, Dudognon, Emeline, Le Fer, Gaëlle, Fournier, David, Woisel, Patrice, Affouard, Frédéric   +5 more
openaire   +4 more sources

An Investigation into the Role of Polymeric Carriers on Crystal Growth within Amorphous Solid Dispersion Systems

, 2015
Using phase diagrams derived from Flory–Huggins theory, we defined the thermodynamic state of amorphous felodipine within three different polymeric carriers.
David S. Jones, Gavin P. Andrews, Jones, David S., Yiwei Tian, Andrews, Gavin P., Tian, Yiwei; id_orcid   +5 more
core   +1 more source

Molecularly Dissipative Liquid Crystal Elastomer Foams for Impact and Vibration Attenuation

Advanced Functional Materials, EarlyView.
Liquid crystal elastomer foams integrate cellular deformation with mesogen reorientation to create a dual‐scale energy dissipation mechanism. Progressive pore collapse absorbs mechanical loads, while stress‐induced mesogen reorientation provides additional damping, resulting in reduced impact transmission and broadband suppression of vibrational ...
Subi Choi, Sangyeop Lee, In‐sun Jeong, Kyungjun Song, Eugene M. Terentjev, Suk‐kyun Ahn   +5 more
wiley   +1 more source

Pharmaceutical technologies for improving drug loading in the formulation of solid dispersions [PDF]

, 2013
textIt is estimated that 90% of new chemical entities in development pipelines exhibit poor aqueous solubility. For compounds not limited by biological membrane permeability, this poor aqueous solubility is the limiting factor in bioavailability ...
O'Donnell, Kevin Patrick
core