Results 81 to 90 of about 2,340,313 (291)

Formulation, Characterization, and in Vivo Evaluation of Celecoxib-PVP Solid Dispersion Nanoparticles Using Supercritical Antisolvent Process

open access: yesMolecules, 2014
The aim of this study was to develop celecoxib-polyvinylpyrrolidone (PVP) solid dispersion nanoparticles with and without surfactant using the supercritical antisolvent (SAS) process.
Eun-Sol Ha   +3 more
doaj   +1 more source

Electrically Induced Phase Transition and Synaptic Functionality in MoTe2/Graphene Memristors

open access: yesAdvanced Functional Materials, EarlyView.
An electrically induced reversible 2H ↔ 1T′ phase transition is demonstrated in a vertical Au/Ti/MoTe2/graphene memristor with a laterally contacted graphene electrode. Resistive switching proceeds through a compositionally invariant amorphous/2H ↔ amorphous/1T′ transformation, in which a self‐formed amorphous MoTe2 interfacial region is proposed to ...
Chien‐Hua Wang   +7 more
wiley   +1 more source

The effects of moisture on pharmaceutical amorphous solid dispersion systems

open access: yes, 2009
Delivery of drugs with low aqueous solubility in the amorphous form can be exploited as a strategy to increase absorption, especially when dissolution is the rate-limiting step. To prevent drug crystallization over pharmaceutically relevant timescales, a
Rumondor, Alfred C. F
core  

Upcycling Keratin‐Based Textile Waste Into High‐Performance Hybrid Fibers Via Tuning the Interfacial Interactions

open access: yesAdvanced Functional Materials, EarlyView.
Keratin recovered from animal‐hair textile waste is fractionated and blended with cellulose to produce continuously spun hybrid fibers. Selecting the high‐molecular‐weight keratin fraction enables 30 wt.% keratin incorporation while maintaining high strength in dry and wet states.
Mian Zhai   +6 more
wiley   +1 more source

Rapid Microwave Plasma Engineering of HfO2/C@C Core‐Shell Fibrous Membrane Toward Flexible High‐Performance Electromagnetic Wave Absorption

open access: yesAdvanced Functional Materials, EarlyView.
Rapid microwave plasma torch engineering tunes crystal phases, carbon graphitization and oxygen‐vacancy defects in HfO2/C@C core‐shell fibrous membranes. Synergistic multi‐loss effects optimize impedance matching to deliver −65.75 dB reflection loss and a 7.37 GHz effective bandwidth for flexible electromagnetic wave absorption.
Qichao Ding   +14 more
wiley   +1 more source

A process for the preparation of amorphous solid dispersion comprising Elacestrant dihydrochloride and Povidone [PDF]

open access: yes
The present disclosure relates to a process for the preparation of amorphous solid dispersion comprising Elacestrant dihydrochloride of formula-1a and ...
, Srinivasan Thirumalai Rajan, Sagyam Rajeshwar Reddy, Kammari Bal Raju, Kamutam Sathish, MSN Laboratories Private Limited, R&D Center, Hyderabad, India.
core  

SOLID DISPERSION: A REVIEW

open access: yes, 2017
The solubility issues complicating the delivery of the new drugs and also affect the delivery of many existing drugs. There are various techniques are available for enhancement of solubility.
M. E. Potkule*, A. D. Savkare, S. K. Sarode, P. S. Kalaskar
core   +1 more source

Self‐Assembled Crystalline Peptoid Nanomaterials as Metal‐Free Enzyme Mimics for Enhanced Carbon Dioxide Hydration and Precipitation

open access: yesAdvanced Functional Materials, EarlyView.
Inspired by metal‐free carbonic anhydrases (CAs) that achieve efficient catalysis without metal cofactors, we herein report a sequence‐defined supramolecular peptoid platform that mimics metal‐free CAs and exhibits hydrolytic activity via a supramolecular assembly‐mediated proton‐transfer mechanism.
Progyateg Chakma   +8 more
wiley   +1 more source

Manufacturing Amorphous Solid Dispersions with Improved Solid-State Stability

open access: yes, 2021
Although amorphous solid dispersion(ASD) is a promising strategy for enhancing drug solubility, it has not been recognized to its full potential due to a lack of understanding as to how solid state stability is affected by manufacturing conditions such as method of preparation, formulation parameters (choice of excipients, drug-polymer ratio ...
openaire   +1 more source

Drug-excipient behavior in polymeric amorphous solid dispersions [PDF]

open access: yes, 2013
Amorphous drug delivery system is being increasingly utilized for enhancing aqueous solubility and oral bioavailability. However it suffers from lack of physical/chemical stability.
Patil, Shashank Pralhad   +4 more
core  

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