Results 201 to 210 of about 118,015 (300)

Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity. [PDF]

Int J Pharm X, 2021
Davis DA, Miller DA, Santitewagun S, Zeitler JA, Su Y, Williams RO.   +5 more
europepmc   +1 more source

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

Advanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source

Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir. [PDF]

Pharmaceutics
Alhamhoom Y, Kumaraswamy T, Kumar A, Nanjappa SH, Prakash SS, Rahamathulla M, Thajudeen KY, Ahmed MM, Shivanandappa TB.   +8 more
europepmc   +1 more source

Automated PET-RAFT Polymerization Towards Pharmaceutical Amorphous Solid Dispersion Development. [PDF]

ACS Appl Polym Mater, 2021
Upadhya R, Punia A, Kanagala MJ, Liu L, Lamm M, Rhodes TA, Gormley AJ.   +6 more
europepmc   +1 more source

Bio‐Inspired Magnetically Tunable Structural Colors from Elliptical Self‐Assembled Block Copolymer Microparticles

Advanced Functional Materials, EarlyView.
Cephalopod‐inspired photonic microparticles with dynamic structural coloration are fabricated via confined self‐assembly of linear block copolymers into ellipsoids containing stacked lamellae. Embedded superparamagnetic nanoparticles enable rapid magnetic alignment, restoring vivid, angle‐dependent color.
Gianluca Mazzotta, Simone Bertucci, Jose Mendoza‐Carreño, Agustín Mihi, Paola Lova, Davide Comoretto, Ullrich Steiner, Marco Lattuada, Andrea Dodero   +8 more
wiley   +1 more source

From formulation to structure: 3D electron diffraction for the structure solution of a new indomethacin polymorph from an amorphous solid dispersion. [PDF]

IUCrJ
Leung HW, Copley RCB, Lampronti GI, Day SJ, Saunders LK, Johnstone DN, Midgley PA.   +6 more
europepmc   +1 more source

Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan. [PDF]

Pharmaceuticals (Basel), 2021
Giri BR, Kwon J, Vo AQ, Bhagurkar AM, Bandari S, Kim DW.   +5 more
europepmc   +1 more source

Dual‐Site Ru Single‐Atoms and RuP Nanoclusters on N, P, and B Co‐Doped Porous Carbon for Efficient Alkaline HER and AEM Water Electrolysis

Advanced Functional Materials, EarlyView.
Ru single atoms and RuP nanoclusters are co‐anchored in N, P, and B co‐doped porous carbon nanospheres via in situ carbonization/phosphidation of a boronate polymer precursor. RuP activates water, while nearby Ru single atoms accelerate H2 formation through H* transfer. The catalyst delivers low overpotential and high durability in alkaline HER and AEM
Xiaohong Wang, Juguo Dai, Dongxu Li, Jianghua Wu, Hucheng Fu, Yiting Xu, Xueqiang Qi, Qian Xue, Yanbin Shen, Xiaoqing Pan, Conghui Yuan, Shuifen Xie, Andreu Cabot, Lizong Dai   +13 more
wiley   +1 more source

Prenucleation Species Dictate Foreign Ion Incorporation in the Biomineral Precursor Amorphous Calcium Carbonate

Advanced Functional Materials, EarlyView.
ACC forms via aggregating prenucleation clusters that gatekeep its chemical composition. Ion identity steers the path: Ba and Sr substitute Ca in clusters, thereby inhibiting nucleation, with a dose‐dependent switch of Sr to induction. Mg partitions into Mg‐rich and Mg‐poor clusters; the latter form ACC, expelling Mg.
Qianyu Zhao, Patrick Duchstein, Benedikt Demmert, Thi Q. Nhi Dao, Krishnaveni Anjala, Evelyn Gruber, Franziska Gröhn, Dirk Zahn, Dorrit E. Jacob, Stephan E. Wolf   +9 more
wiley   +1 more source

Trends in amorphous solid dispersion drug products approved by the U.S. Food and Drug Administration between 2012 and 2023. [PDF]

Int J Pharm X
Moseson DE, Tran TB, Karunakaran B, Ambardekar R, Hiew TN.   +4 more
europepmc   +1 more source