Results 91 to 100 of about 88,309 (267)
Seizure control by decanoic acid through direct AMPA receptor inhibition
Brain : a journal of neurology, 2015 See Rogawski (doi:10.1093/awv369) for a scientific commentary on this article. The MCT ketogenic diet, an established treatment for drug-resistant epilepsy, leads to an elevation of plasma decanoic acid and ketones. Chang et al. show that decanoic acid,
P. Chang +9 more
semanticscholar +1 more source
Modulating Excitatory Synaptic Neurotransmission: Potential Treatment for Neurological Disease?
Neurobiology of Disease, 1998 Excitatory neurotransmission at many CNS synapses depends upon AMPA-type glutamate receptors. Derangements in AMPA receptor-mediated synaptic transmission may be a contributing factor in neurological and neurodegenerative diseases and could be a target ...
Kelvin A. Yamada
doaj
Ecotoxicology and Environmental Safety, 2022 Glyphosate and its metabolite aminomethylphosphonic acid (AMPA) draw great concern due to their potential threat to aquatic ecosystems. The individual and combined effects of glyphosate and AMPA on aquatic plants in different ecological niches need to be
Mengjie Qu +5 more
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Potential wells for AMPA receptors organized in ring nanodomains [PDF]
arXiv, 2013 By combining high-density super-resolution imaging with a novel stochastic analysis, we report here a peculiar nano-structure organization revealed by the density function of individual AMPA receptors moving on the surface of cultured hippocampal dendrites.
arxiv
PLoS ONE, 2017 S 47445 is a novel positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors (AMPA-PAM). S 47445 enhanced glutamate's action at AMPA receptors on human and rat receptors and was inactive at NMDA and ...
Sylvie Bretin +18 more
doaj +1 more source
A neuroeconomic theory of bidirectional synaptic plasticity and addiction [PDF]
arXiv, 2011 Neuronal mechanisms underlying addiction have been attracting attention in neurobiology, economics, neuropsychiatry, and neuroeconomics. This paper proposes a possible link between economic theory of addiction (Becker and Murphy, 1988) and neurobiological theory of bidirectional synaptic plasticity (Bienenstock, Cooper, Munro, 1982) based on recent ...
arxiv
Scientific Reports, 2016 Both TDP-43 pathology and failure of RNA editing of AMPA receptor subunit GluA2, are etiology-linked molecular abnormalities that concomitantly occur in the motor neurons of the majority of patients with amyotrophic lateral sclerosis (ALS).
Megumi Akamatsu +4 more
semanticscholar +1 more source
Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
Cell Reports, 2023 Summary: The recruitment of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors underlies the strengthening of neuronal connectivity during learning and memory. This process is triggered by N-methyl-D-aspartate (NMDA) receptor-
Jing Zhi Anson Tan +10 more
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Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition
Nature, 2021 Jie Yu +5 more
semanticscholar +1 more source
Toxicity of AMPA to the earthworm Eisenia andrei Bouché, 1972 in tropical artificial soil
Scientific Reports, 2016 Aminomethylphosphonic acid (AMPA) - one of glyphosate’s main metabolites - has been classified as persistent in soils, raising concern regarding the widespread use of glyphosate in agriculture and forestry. Glyphosate may have negative or neutral effects
A. Domínguez +7 more
semanticscholar +1 more source