Results 121 to 130 of about 159,111 (333)
AMPA experimental communications systems [PDF]
The program was conducted to demonstrate the satellite communication advantages of Adaptive Phased Array Technology. A laboratory based experiment was designed and implemented to demonstrate a low earth orbit satellite communications system.
Beckerman, D.+3 more
core +1 more source
Novel Anchorage of GluR2/3 to the Postsynaptic Density by the AMPA Receptor–Binding Protein ABP [PDF]
Shalini Srivastava+11 more
openalex +1 more source
Abstract Objective This study was undertaken to determine how voltage‐gated sodium channel (VGSC) blockers modulate cortical excitability in vivo. VGSCs are critical for regulating axonal excitability, yet the effects of sodium channel‐blocking medications on human cortical neurons remain poorly characterized.
Lorenzo Rocchi+6 more
wiley +1 more source
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire+9 more
wiley +1 more source
The AMPA Receptor Code of Synaptic Plasticity
Graham H. Diering, R. Huganir
semanticscholar +1 more source
What Epigenetics Teaches Us About Neuron-Glioma Interactions. [PDF]
Neuron–glioma interactions through the epigenetic lens. Rewiring of epigenetic mechanisms, including alterations in the enhancer landscape and 3D chromatin organization, allows glioma cells to sense and respond to neural signals. Targeting the epigenetic machinery that facilitates this neuron–glioma crosstalk provides a strategy to disrupt the neural ...
Chakraborty C, Nissen I, Remeseiro S.
europepmc +2 more sources
Abstract Objective Current preclinical epilepsy drug screening relies on animal models that poorly reflect human neurophysiology, leading to high failure rates in clinical translation. We aimed to establish a human in vitro model using human‐induced pluripotent stem cell (hiPSC)–derived cortical neurons cultured on multielectrode arrays (MEAs), capable
Joshua Nicholls+13 more
wiley +1 more source
Persistent phosphorylation parallels long-term desensitization of cerebellar purkinje cell AMPA-type glutamate receptors. [PDF]
Kazu Nakazawa, Sumiko Mikawa, M. Ito
openalex +1 more source
Topiramate for the treatment of neonatal seizures and beyond
Abstract Acute symptomatic neonatal seizures are one of the most common neurological disorders in newborns admitted to neonatal intensive care units and require prompt treatment. Up to 50% of neonatal seizures are refractory to first‐line medications such as phenobarbital (PB), and another 30% fail second‐line therapy.
Wolfgang Löscher, Janet S. Soul
wiley +1 more source