Results 51 to 60 of about 150,350 (378)
Frontiers in Synaptic Neuroscience, 2021 The amygdala plays a crucial role in attaching emotional significance to environmental cues. Its intercalated cell masses (ITC) are tight clusters of GABAergic neurons, which are distributed around the basolateral amygdala complex.
Anna Seewald +6 more
doaj +1 more source
Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum
Neuroscience, 2009 Heterogeneity among AMPA receptor (AMPAR) subtypes is thought to be one of the key postsynaptic factors giving rise to diversity in excitatory synaptic signaling in the CNS. Recently, compelling evidence has emerged that ancillary AMPAR subunits-the so-called transmembrane AMPA receptor regulatory proteins (TARPs)-also play a vital role in influencing ...
Ian D. Coombs, Stuart G. Cull-Candy
openaire +3 more sources
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
Nature, 2017 AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid)-subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission throughout the central nervous system.
E. C. Twomey +4 more
semanticscholar +1 more source
AMPA receptor biogenesis and trafficking
Current Opinion in Neurobiology, 2007 AMPA-type glutamate receptors mediate the majority of fast excitatory transmission in the central nervous system. The trafficking of AMPA receptors to and from synapses alters synaptic strength and has been recognized as a central mechanism underlying various forms of synaptic plasticity.
Greger, Ingo H., Esteban, José A.
openaire +4 more sources
Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices
Scientific Reports, 2023 Pharmacologically-induced persistent hippocampal γ oscillation in area CA3 requires activation of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs). However, we demonstrated that exogenous AMPA dose-dependently inhibited carbachol (CCH)-
Chengzhang Li +11 more
doaj +1 more source
Synapse elimination and learning rules co-regulated by MHC class I H2-Db. [PDF]
, 2014 The formation of precise connections between retina and lateral geniculate nucleus (LGN) involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the major histocompatibility complex (MHC)
Adelson, Jaimie +7 more
core +3 more sources
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 421-429, December 2022., 2022 Abstract Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the glutamatergic system.
Ahmad Shamabadi
wiley +1 more source
Degradation of Glyphosate to Benign N‐Formyl Glycine Using MOF‐808 Nanocrystals
Angewandte Chemie, EarlyView.A Zr‐based metal–organic framework (MOF‐808) with different crystal sizes and designed defect sites was employed as an efficient heterogeneous catalyst for the complete degradation of glyphosate at room temperature. The degradation mechanism produces N‐formyl glycine and hydroxymethyl‐phosphonate. Abstract Glyphosate (N‐phosphonomethyl glycine, GPh) is
Jhair A. Peña Prada +6 more
wiley +2 more sources
Extracts of edible, medicinal Thai plants inhibit the human breast cancer cells [PDF]
, 2020 Purpose: To evaluate the effects of ten edible, medicinal Thai plant extracts on MCF-7 cell viability and cell migration, as well as their mechanism(s) of action.
Buranrat, Benjaporn +2 more
core +2 more sources
Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP
Nature, 2017 Strengthening of synaptic connections by NMDA (N-methyl-d-aspartate) receptor-dependent long-term potentiation (LTP) shapes neural circuits and mediates learning and memory.
Dick Wu +8 more
semanticscholar +1 more source