Results 51 to 60 of about 2,263,243 (98)
Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains
eLife, 2017 Ion conductivity and the gating characteristics of tetrameric glutamate receptor ion channels are determined by their subunit composition. Competitive homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling assembly.
Huaying Zhao +5 more
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Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition
Nature, 2021 Jie Yu +5 more
semanticscholar +1 more source
Disease Models & Mechanisms, 2019 Loss-of-function mutations in a human AMPA receptor-associated protein, ferric chelate reductase 1-like (FRRS1L), are associated with a devastating neurological condition incorporating choreoathetosis, cognitive deficits and epileptic encephalopathies ...
Michelle Stewart +12 more
doaj +1 more source
Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons
Journal of Neuroscience, 1996 The AMPA receptor, which is involved in most fast glutamatergic transmission in the mammalian brain and is expressed in most neurons, is made up of four subunits, GluR1–4.
R. Wenthold +3 more
semanticscholar +1 more source
LTD expression is independent of glutamate receptor subtype
Frontiers in Synaptic Neuroscience, 2014 Long-term depression (LTD) is a form of synaptic plasticity that plays a major role in the activity-dependent reshaping of synaptic transmission.
Adam J Granger, Roger A Nicoll
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Differential Regulation of AMPA Receptor and GABA Receptor Trafficking by Tumor Necrosis Factor-α
Journal of Neuroscience, 2005 The proinflammatory cytokine tumor necrosis factor-α (TNFα) causes a rapid exocytosis of AMPA receptors in hippocampal pyramidal cells and is constitutively required for the maintenance of normal surface expression of AMPA receptors.
D. Stellwagen +3 more
semanticscholar +1 more source
Psychostimulant-induced neuroadaptations in nucleus accumbens AMPA receptor transmission.
Cold Spring Harbor Perspectives in Medicine, 2013 Medium spiny neurons of the nucleus accumbens serve as the interface between corticolimbic regions that elicit and modulate motivated behaviors, including those related to drugs of abuse, and motor regions responsible for their execution.
R. Pierce, M. Wolf
semanticscholar +1 more source
SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons
Neuroscience ResearchLong-term depression (LTD) is a form of synaptic plasticity thought to be the cellular basis of experience-dependent learning and memory. LTD is caused by an activity-dependent decrease in cell surface α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Misaki Morishita, Shinji Matsuda
doaj
Molecular & Cellular Proteomics, 2013 The cysteine protease caspase-3, best known as an executioner of cell death in apoptosis, also plays a non-apoptotic role in N-methyl-d-aspartate receptor-dependent long-term depression of synaptic transmission (NMDAR-LTD) and α-amino-3-hydroxy-5-methyl ...
Mengna Han +7 more
semanticscholar +1 more source
Expression of AMPA and NMDA receptor subunits in the cervical spinal cord of wobbler mice
BMC Neuroscience, 2006 Background The localisation of AMPA and NMDA receptor subunits was studied in a model of degeneration of cervical spinal motoneurons, the wobbler mouse. Cervical regions from early or late symptomatic wobbler mice (4 or 12 weeks of age) were compared to ...
Corsi Massimiliano M +8 more
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