Results 81 to 90 of about 2,263,243 (98)

Preclinical pharmacology of perampanel, a selective non‐competitive AMPA receptor antagonist

Acta Neurologica Scandinavica, Supplementum, 2013
Michael A. Rogawski, Takahisa Hanada
semanticscholar   +1 more source

The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites

Proceedings of the National Academy of Sciences of the United States of America, 2013
K. Kohda, W. Kakegawa, S. Matsuda, Tadashi Yamamoto, H. Hirano, M. Yuzaki   +5 more
semanticscholar   +1 more source

Enhanced AMPA receptor activity increases operant alcohol self‐administration and cue‐induced reinstatement

Addiction Biology, 2013
R. Cannady, Kristen R. Fisher, Brandon K. Durant, J. Besheer, C. Hodge   +4 more
semanticscholar   +1 more source

Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression

Nature Communications, 2013
S. Matsuda, W. Kakegawa, Timotheus Budisantoso, Toshihiro Nomura, K. Kohda, M. Yuzaki   +5 more
semanticscholar   +1 more source

AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting

Proceedings of the National Academy of Sciences of the United States of America, 2013
P. Hastie, Maximilian H. Ulbrich, Hui-Li Wang, R. Arant, A. Lau, Zhenjie Zhang, E. Isacoff, Lu Chen   +7 more
semanticscholar   +1 more source

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AMPA receptor trafficking and synaptic plasticity.

Annual Review of Neuroscience, 2002
Activity-dependent changes in synaptic function are believed to underlie the formation of memories. Two prominent examples are long-term potentiation (LTP) and long-term depression (LTD), whose mechanisms have been the subject of considerable scrutiny ...
R. Malinow, R. Malenka
semanticscholar   +1 more source

Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking.

Annual Review of Physiology, 2016
For more than 20 years, we have known that Ca(2+)/calmodulin-dependent protein kinase (CaMKII) activation is both necessary and sufficient for the induction of long-term potentiation (LTP). During this time, tremendous effort has been spent in attempting
B. Herring, R. Nicoll
semanticscholar   +1 more source

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.

Journal of Medicinal Chemistry, 2016
Transmembrane AMPA receptor regulatory proteins (TARPs) are a family of scaffolding proteins that regulate AMPA receptor trafficking and function. TARP γ-8 is one member of this family and is highly expressed within the hippocampus relative to the ...
K. Gardinier, D. Gernert, Warren J. Porter, J. Reel, P. Ornstein, P. Spinazze, F. Craig Stevens, P. Hahn, S. Hollinshead, D. Mayhugh, J. Schkeryantz, A. Khilevich, Ó. de Frutos, S. Gleason, Akihiko S. Kato, D. Luffer-Atlas, Prashant V. Desai, S. Swanson, Kevin D. Burris, Chunjin Ding, Beverly A. Heinz, A. Need, V. Barth, Gregory A. Stephenson, B. Diseroad, Tim A. Woods, Hong Yu, D. Bredt, J. Witkin   +28 more
semanticscholar   +1 more source

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

Journal of Proteome Research, 2014
Fast excitatory synaptic transmission in the brain is mediated by glutamate acting on postsynaptic AMPA receptors. Recent studies have revealed a substantial number of AMPA receptor auxiliary proteins, which potentially contribute to the regulation of ...
N. Chen, N. Pandya, F. Koopmans, Violeta Castelo-Székelv, R. C. van der Schors, A. Smit, K. Li   +6 more
semanticscholar   +1 more source

The cell biology of synaptic plasticity: AMPA receptor trafficking.

Annual Review of Cell and Developmental Biology, 2007
The cellular processes that govern neuronal function are highly complex, with many basic cell biological pathways uniquely adapted to perform the elaborate information processing achieved by the brain.
J. Shepherd, R. Huganir
semanticscholar   +1 more source