Results 161 to 170 of about 86,925 (261)

AMPA Receptors in NG2 Glia Differently Affect Signal Transduction in the Hippocampus and Cerebellum. [PDF]

Glia
Tascio D, Gebril N, Jabs R, Henneberger C, Steinhäuser C, Seifert G.   +5 more
europepmc   +1 more source

Evaluating Protein Enrichment Methods to Improve Biomarker Discovery in Equine Cerebrospinal Fluid

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Here, we compared two protein enrichment methods—ProteoMiner Small‐Capacity and PreOmics Enrich‐iST—for proteomic analysis of equine cerebrospinal fluid (CSF). PreOmics Enrich‐iST achieved superior depletion of high‐abundance proteins and identified a greater number of low‐abundance, neuropathology‐relevant proteins than ProteoMiner or native digestion.
Foti Federico, Wilson Amie, Chabronova Alzbeta, Jensen Anders, Lunn Paul David, Peffers Jayne Mandy   +5 more
wiley   +1 more source

The Role of Calcium-Permeable Kainate and AMPA Receptors in the Leading Reaction of GABAergic Neurons to Excitation. [PDF]

Curr Issues Mol Biol
Zinchenko VP, Kosenkov AM, Sergeev AI, Tyurin FV, Turovsky EA, Kairat BK, Malibayeva AE, Tussupbekova GA, Tuleukhanov ST.   +8 more
europepmc   +1 more source

Fasting and Caloric Restriction Activate an ADIOL‐NHR‐91‐Kynurenine Pathway Signaling Axis to Promote Healthspan

Aging Cell, Volume 25, Issue 5, May 2026.
The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández, Shinja Yoo, George A. Lemieux, Sena Komatsu, Abdullah Q. Latiff, Rishika R. Patil, Kaveh Ashrafi   +6 more
wiley   +1 more source

AMPA receptors in the evolving synapse: structure, function, and disease implications. [PDF]

Front Synaptic Neurosci
Francis F, Chettri D, Nair D.
europepmc   +1 more source

Systematic Multiplatform Discovery of Methylation Markers Enables Non‐Invasive Early Detection of Endometrial Cancer

Cancer Science, Volume 117, Issue 5, Page 1412-1421, May 2026.
We identified key endometrial cancer DNA methylation biomarkers (ZNF626, GRIA4, SPDYA) from cervical cells. The model achieved high endometrial cancer sensitivity and detected 92.86% of Stage I endometrial cancers using TCT samples. ABSTRACT Endometrial cancer, the most common gynecological malignancy with an annual increase of 1%–3%, lacks suitable ...
Yan Cai, Shuchao Chen, Zhen Wu, Jinxia Guan, Jie Zhao, Jianwei Ye, Baochen Du, Xiaoliang Han, Tong Shu, Guangpeng Zhou, Hong Zheng   +10 more
wiley   +1 more source

O-GlcNAcase promotes dendritic spine morphogenesis while downregulating their GluA2-containing AMPA receptors. [PDF]

J Biol Chem
Han L, Galizia S, Pan J, Bhattacharjee M, Lagerlöf O.   +4 more
europepmc   +1 more source

Subunit-specific expression and function of AMPA receptors in the mouse locus coeruleus. [PDF]

J Anat, 2023
Kelly L, Brown C, Gibbard AG, Jackson T, Swinny JD.   +4 more
europepmc   +1 more source

The Effect of the Anticonvulsant Topiramate on Acetylcholine‐Induced Calcium Signals is Linked to Sirt‐1 Activity

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
This work provides a potential new link between the anticonvulsive Topiramate, the deacetylase Sirt‐1 and the cholinergic signalling, suggesting that Topiramate may modulate cholinergic pathways in a Sirt‐1 depended manner. ABSTRACT Although some forms of epilepsy directly result from mutations in nicotinic acetylcholine receptors, none of the ...
Marie‐Luise Kümmel
wiley   +1 more source

Memantine inhibits calcium-permeable AMPA receptors. [PDF]

Nat Commun
Carrillo E, Montaño Romero A, Gonzalez CU, Turcu AL, Vázquez S, Twomey EC, Jayaraman V.   +6 more
europepmc   +1 more source