Results 201 to 210 of about 2,315,831 (319)

Delayed Antagonism of AMPA/Kainate Receptors Reduces Long-Term Functional Deficits Resulting from Spinal Cord Trauma

, 1997
Jean R. Wrathall, Chaoho Ouyang, Robert Marriott   +2 more
openalex   +1 more source

Natural aminosterols inhibit NMDA receptors with low nanomolar potency

The FEBS Journal, Volume 292, Issue 13, Page 3521-3544, July 2025.
Misfunction of N‐methyl‐D‐aspartate (NMDA) receptors is associated with many brain disorders, making them primary targets for drug discovery. Trodusquemine and other natural aminosterols inhibit NMDA receptors with low nanomolar potency through binding to the cell membranes followed by interaction with the channels.
Giulia Fani, Elisabetta Coppi, Silvia Errico, Federica Cherchi, Martina Gennari, Denise Barbut, Michele Vendruscolo, Michael Zasloff, Anna Maria Pugliese, Fabrizio Chiti   +9 more
wiley   +1 more source

Recent Insights into the Functional Role of AMPA Receptors in the Oligodendrocyte Lineage Cells In Vivo. [PDF]

Int J Mol Sci, 2023
Kukley M.
europepmc   +1 more source

Regulation of Kinetic Properties of GluR2 AMPA Receptor Channels by Alternative Splicing [PDF]

, 2000
Maki Koike‐Tani, Shota Tsukada, Keisuke Tsuzuki, Hiromasa Kijima, Seiji Ozawa   +4 more
openalex   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, Volume 28, Issue 23, June 23, 2025.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Amyloid-β-Driven Synaptic Deficits Are Mediated by Synaptic Removal of GluA3-Containing AMPA Receptors. [PDF]

J Neurosci
Reinders NR, van der Spek SJF, Klaassen RV, Koymans KJ, MacGillavry HD, Smit AB, Kessels HW.   +6 more
europepmc   +1 more source

The Lurcher Mutation Identifies δ2 as an AMPA/Kainate Receptor-Like Channel That Is Potentiated by Ca²⁺ [PDF]

, 2000
Lonnie P. Wollmuth, Thomas Kuner, Claudia Jatzke, Peter H. Seeburg, Nathaniel Heintz, Jian Zuo   +5 more
openalex   +1 more source

Positive allosteric modulation of AMPA receptors via PF4778574 leads to reduced demyelination and clinical disability in experimental models of multiple sclerosis. [PDF]

Front Immunol
Sindi M, Dietrich M, Klees D, Gruchot J, Hecker C, Silbereis J, Issberner A, Hartung HP, Ruck T, Stark H, Kurz T, Küry P, Meuth SG, Albrecht P.   +13 more
europepmc   +1 more source

GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors. [PDF]

iScience, 2023
Nair JD, Wilkinson KA, Yucel BP, Mulle C, Vissel B, Mellor J, Henley JM.   +6 more
europepmc   +1 more source

Inhibition by adenosine A_2A receptors of NMDA but not AMPA currents in rat neostriatal neurons [PDF]

, 2000
Kerstin Wirkner, Heike Aßmann, László Köles, Zoltán Gerevich, Heike Franke, Wolfgang Nörenberg, Rudolf Bœhm, Péter Illés   +7 more
openalex   +1 more source