Results 201 to 210 of about 53,245 (286)

Creation of a biophysical model of a striatal dorsal lateral medium spiny neuron incorporating dendritic excitation by NMDA and AMPA receptor models.

, 2007
Kevin M. Biddell
openalex   +1 more source

Cross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Trafficking [PDF]

, 2016
Roy S. Song, Rosa E. Tolentino, Eric A. Sobie, Susana R. Neves   +3 more
openalex   +1 more source

Electrical Synapses Contribute to Sleep‐Dependent Declarative Memory Retention

European Journal of Neuroscience, Volume 63, Issue 2, January 2026.
Blocking electrical synapses (gap junctions) in healthy humans by mefloquine impaired the sleep‐dependent retention of verbal declarative memory and improved sensorimotor memory consolidation irrespective of sleep. Mefloquine also disrupted the coupling of sleep spindles to EEG slow oscillations in humans but did not affect hippocampal sharp‐wave ...
Gordon B. Feld, Niels Niethard, Jianfeng Liu, Sandra Gebhardt, Lisa Kleist, Kerstin Brugger, Andreas Fritsche, Jan Born, Hong‐Viet V. Ngo, Manfred Hallschmid   +9 more
wiley   +1 more source

Prolonged esophageal acid exposures induce synaptic downscaling of cortical membrane AMPA receptor subunits in rats

, 2016
Banani Banerjee, Bidyut K. Medda, J. Zhang, Vishwajit J. Tuchscherer, Reji Babygirija, Pradeep Kannampalli, Jyoti N. Sengupta, Reza Shaker   +7 more
openalex   +1 more source

Sevoflurane Inhibits Layer 5 Pyramidal Neurons via Kv1.2‐Dependent Modulation of Subthreshold Currents

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
General anesthetics suppress cortical activity, but their cellular mechanisms remain unclear. We investigated how the volatile anesthetic sevoflurane affects layer 5 pyramidal neurons in the auditory cortex. Using patch‐clamp recordings and computational modeling, we found that low‐dose sevoflurane reduces neuronal firing through Kv1.2 channel ...
Aelton S. Araujo, Gabriel M. de Queiroz, Sérgio Ruschi B. Silva, Werner Treptow, Katarina E. Leao   +4 more
wiley   +1 more source

Optogenetic stimulation of the median preoptic nucleus: Effects on hypothalamic paraventricular nucleus magnocellular neurons after chronic intermittent hypoxia exposure

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Median preoptic nucleus (MnPO) neurons projecting to the hypothalamic paraventricular nucleus (PVN) are linked to hypertension induced by chronic intermittent hypoxia (CIH), a model of obstructive sleep apnea. The modulation of MnPO‐driven synaptic activity in PVN magnocellular neurons (MNCs) by CIH remains unexamined.
Obed T. Paundralingga, Shuping Jia, George E. Farmer Jr, Glenn M. Toney, J. Thomas Cunningham   +4 more
wiley   +1 more source

Ketamine Reverses Chronic Stress-Induced Behavioral Changes via the Expression of Ca²⁺-Permeable AMPA Receptors in Mice. [PDF]

FASEB J
Flowers JC, Vetter PE, Wiles MJ, Roh SH, Black ER, Bouckova E, Wustrau MH, Lee R, Lee SH, Kim S.   +9 more
europepmc   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

The Journal of Physiology, Volume 604, Issue 2, Page 689-706, 15 January 2026.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Roles of AMPA receptors in social behaviors. [PDF]

Front Synaptic Neurosci
Xu QW, Larosa A, Wong TP.
europepmc   +1 more source

Generalised Hodgkin–Huxley model captures human P2X and AMPA receptor currents

The Journal of Physiology, Volume 604, Issue 1, Page 214-246, 1 January 2026.
Abstract figure legend A universal, biophysically interpretable mathematical model for human ionotropic receptors. The generalised Hodgkin–Huxley (gHH) model unifies the mathematical description of all major ligand‐gated ionotropic receptors (P2X1–7, AMPA) across diverse cell types, capturing activation, inactivation, desensitisation and recovery ...
Alireza Poshtkohi, Brian D. Gulbransen
wiley   +1 more source