Results 11 to 20 of about 14,068 (191)

Salicylate decreases production of AmpC type β-lactamases and increases susceptibility to β-lactams in aMorganella morganiiclinical isolate [PDF]

FEMS Microbiology Letters, 2004
The effect of salicylate, a marRAB inducer, on the resistance to β-lactams was characterized in an AmpC β-lactamase hyperproducer Morganella morganii clinical isolate (the M1 strain). Results were compared with those of the effect of salicylate in a wild-type M. morganii strain.
María M. Tavío, Mariagrazia Perilli, Jordi Vila, Pino Becerro, Lucía Casañas, Gianfranco Amicosante, María Teresa Jiménez de Anta   +6 more
openaire   +1 more source

Outbreak ofKlebsiella pneumoniaeproducing transferable AmpC-type β-lactamase (ACC-1) originating fromHafnia alvei [PDF]

FEMS Microbiology Letters, 2000
Fifty-two strains of Klebsiella pneumoniae producing an AmpC-type plasmid-mediated beta-lactamase were isolated from 13 patients in the same intensive care unit between March 1998 and February 1999. These strains were resistant to ceftazidime, cefotaxime and ceftriaxone, but susceptible to cefoxitin, cefepime and aztreonam.
D, Nadjar, M, Rouveau, C, Verdet, L, Donay, J, Herrmann, P H, Lagrange, A, Philippon, G, Arlet   +7 more
openaire   +2 more sources

Diversity of chromosomal AmpC β-lactamases fromEnterobacter cloacaeisolates in a Portuguese hospital [PDF]

FEMS Microbiology Letters, 2004
Six clinical isolates of Enterobacter cloacae isolated in a Portuguese hospital, between April 1999 and November 2000, demonstrated resistance to almost all broad-spectrum cephalosporins, except to cefepime. These isolates were susceptible to quinolones and to aminoglycosides. Isoelectric focusing demonstrated production of beta-lactamases with pIs > 8.
Conceicao, T, Faria, N, Lito, L, Cristino, JM, Salgado, MJ, Duarte, A   +5 more
openaire   +3 more sources

Investigation of thePseudomonas aeruginosa ampRgene and its role at the chromosomalampCβ-lactamase promoter [PDF]

FEMS Microbiology Letters, 1993
The complete sequence of the Pseudomonas aeruginosa beta-lactamase regulator gene ampR has been determined. The amino acid sequence encoded by this gene is compared with other members of the LysR family of transcription factors. The P. aeruginosa ampC promoter was subcloned and gel mobility shift assays were used to demonstrate specific binding of AmpR
J, Lodge, S, Busby, L, Piddock
openaire   +2 more sources

Characterisation of CMY-4, an AmpC-type plasmid-mediated β-lactamase in a Tunisian clinical isolate ofProteus mirabilis [PDF]

FEMS Microbiology Letters, 1998
A strain of Proteus mirabilis resistant to beta-lactams, including cefoxitin, was isolated from the urine of a woman from Tunisia. Its antibiotic susceptibility pattern and that of the Escherichia coli transconjugant suggested the presence of an AmpC-type beta-lactamase. Two bands of beta-lactamase activity (pI 5.4 and 9.2) were detected by isoelectric
C, Verdet, G, Arlet, S, Ben Redjeb, A, Ben Hassen, P H, Lagrange, A, Philippon   +5 more
openaire   +2 more sources

Mutations in theampCpromoter ofEscherichia coliisolates resistant to oxyiminocephalosporins without extended spectrum β-lactamase production [PDF]

FEMS Microbiology Letters, 1999
Escherichia coli strains showing an increased resistance to oxyiminocephalosporins without an extended spectrum beta-lactamase production have been screened for mutations in their ampC beta-lactamase gene promoter. Mutations were found by direct sequencing of seven promoters at positions -42, -32 (box -35), -18, -1, +5, +24 (attenuator), +31 ...
N, Caroff, E, Espaze, I, Bérard, H, Richet, A, Reynaud   +4 more
openaire   +2 more sources

Plasmid typing and genetic context of AmpC β-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes: findings from a Spanish hospital 1999–2007 [PDF]

Journal of Antimicrobial Chemotherapy, 2011
To gain insights into ampC transmission between bacterial strains.We examined the genetic context of 117 acquired ampC genes from 27119 Enterobacteriaceae collected between 1999 and 2007. Plasmid analysis was carried out by PCR-based replicon or relaxase typing, S1-PFGE and Southern hybridization.
Mata, Caterina, Miro, Elisenda, Alvarado, Andres, Garcillan-Barcia, M. Pilar, Toleman, Mark, Walsh, Timothy R., de la Cruz, Fernando, Navarro, Ferran   +7 more
openaire   +5 more sources

High prevalence of blaCMY AmpC beta-lactamase in ESBL co-producing Escherichia coli and Klebsiella spp. clinical isolates in the northeast of Iran

Journal of Global Antimicrobial Resistance, 2020
Objective: The production of β-lactamase enzymes such as AmpC β-lactamases and extended-spectrum β-lactamases (ESBLs) is among the main mechanisms for resistance to expanded-spectrum cephalosporins.
Kobra Salimiyan Rizi, Arman Mosavat, Masoud Youssefi, Saeid Amel Jamehdar, Kiarash Ghazvini, Hadi Safdari, Yousef Amini, Hadi Farsiani   +7 more
doaj   +1 more source

Multidrug-resistantPseudomonas aeruginosastrains harbouring R-plasmids and AmpC β-lactamases isolated from hospitalised burn patients in a tertiary care hospital of North India [PDF]

FEMS Microbiology Letters, 2003
The present study was designed to determine resistance rates and patterns in Pseudomonas aeruginosa isolates obtained from hospitalised burn patients in an Indian tertiary care hospital. To that end, we isolated plasmid(s) from the multidrug-resistant isolates, demonstrated the plasmid-mediated resistance by curing and transformation experiments, and ...
M, Shahid, Abida, Malik, , Sheeba
openaire   +2 more sources

Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]

, 2020
Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen, Bedernjak, Alexandre F., Cummings, Stephen P., Day, Kathryn M., Gray, Mark, Jones, Amanda L., Marrs, Emma C.L., Perry, John D., Varadi, Linda   +8 more
core   +2 more sources