Results 11 to 20 of about 381,413 (281)
Self-assembled Structures from Amphiphilic Peptides [PDF]
CHIMIA, 2013 Nanotechnology and its applications are strongly influenced by structures self-assembled from a variety of different materials. This review covers nanostructures, including micelles, rod-like micelles, fibers and peptide beads, self-assembled ...
Severin J. Sigg +2 more
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Amphiphilic Peptides for Efficient siRNA Delivery. [PDF]
Polymers (Basel), 2019 A number of amphiphilic cyclic peptides—[FR]4, [WR]5, and [WK]5—containing hydrophobic and positively-charged amino acids were synthesized by Fmoc/tBu solid-phase peptide methods and evaluated for their efficiency in intracellular delivery of siRNA to triple-negative breast cancer cell lines, MDA-MB-231 and MDA-MB-468, in the presence and absence of 1 ...
Mozaffari S +9 more
europepmc +7 more sources
Journal of Chemical Engineering of Japan, 2023 We previously reported that amphiphilic peptides containing one Lys and two His in the hydrophilic domain—KHHAAAAAA7 (KHHA7)—formed ternary complexes with intermediate metal ions and a poorly water-soluble anticancer drug—paclitaxel (Ptx)—which improved ...
Asuka Inada +2 more
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Self-assembly of amphiphilic peptides [PDF]
Soft Matter, 2011 The self-assembly of amphiphilic peptides is reviewed. The review covers surfactant-like peptides with amphiphilicity arising from the sequence of natural amino acids, and also peptide amphiphiles (PAs) in which lipid chains are attached to hydrophilic peptide sequences containing charged residues.
Hamley, Ian, I. W. Hamley
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A Matter of Charge: Electrostatically Tuned Coassembly of Amphiphilic Peptides. [PDF]
SmallCoassembly of peptide biomaterials offers a compelling avenue to broaden the spectrum of hierarchically ordered supramolecular nanoscale structures that may be relevant for biomedical and biotechnological applications.
Arad E +8 more
europepmc +4 more sources
Peptide based amphiphiles [PDF]
Chem. Soc. Rev., 2004 Contains fulltext : 59199.pdf (Publisher’s version ) (Open Access)
Lowik, D.W.P.M., Hest, J.C.M. van
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Membranes, 2022 Functional peptides are now widely used in a myriad of biomedical and clinical contexts, from cancer therapy and tumor targeting to the treatment of bacterial and viral infections.
Ester Canepa +4 more
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Pharmaceutics, 2022 Extensive effort has been devoted to developing new clinical therapies based on membrane-active peptides (MAPs). Previous models on the membrane action mechanisms of these peptides mostly focused on the MAP–membrane interactions in a local region, while ...
Yujiang Dou +4 more
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Molecular simulations of peptide amphiphiles [PDF]
Organic & Biomolecular Chemistry, 2017 This review describes recent progress in the area of molecular simulations of peptide assemblies, including peptide-amphiphiles, and drug-amphiphiles.
Anjela Manandhar +4 more
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Membranolytic Mechanism of Amphiphilic Antimicrobial β-Stranded [KL]n Peptides
Biomedicines, 2022 Amphipathic peptides can act as antibiotics due to membrane permeabilization. KL peptides with the repetitive sequence [Lys-Leu]n-NH2 form amphipathic β-strands in the presence of lipid bilayers.
Fabian Schweigardt +7 more
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