Results 21 to 30 of about 381,413 (281)
Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides. [PDF]
Medchemcomm, 2018 A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Silva Nigenda E +7 more
europepmc +2 more sources
Cholesterol-peptide hybrids to form liposome-like vesicles for gene delivery. [PDF]
PLoS ONE, 2013 In this paper, four amphiphilic cholesterol-peptide conjugates (Ch-R5H5, Ch-R3H3, Ch-R5 and Ch-R5) were designed and synthesized, and their properties in gene delivery were evaluated in vitro with an aim of developing more efficient gene delivery ...
Qiong Tang +3 more
doaj +1 more source
Dual mechanism β-amino acid polymers promoting cell adhesion
Nature Communications, 2021 Cell adhesion peptides like RGD are important to biomedical applications but suffer from proteolysis as well as processing and cost issues. Here, the authors report on the development of cationic-hydrophobic amphiphilic β-amino acid polymers which ...
Qi Chen +8 more
doaj +1 more source
Review of Nanostructures Formed by Peptide Amphiphiles [PDF]
Nanoscale and Advanced MaterialsPeptides are short-chains of amino acids that have an important role in nature regarding their activities for many biological functions, such as controlling metabolism.
Saeed Balalaie, Vaezeh Fathi Vavsari
doaj +1 more source
Advanced Science, 2020 Finding an effective therapeutic regimen is an urgent demand for various neurodegenerative disorders including Huntington's disease (HD). For the difficulties in observing the dynamic aggregation and oligomerization process of mutant Huntingtin (mHtt) in
Ruei‐Yu He +10 more
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Toxins, 2022 Spider venom is a complex mixture of bioactive components. Previously, we identified two linear peptides in Lycosa poonaensis venom using mass spectrometric analysis and predicted the presence of more linear peptides therein.
Alhussin Mohamed Abdelhakeem Megaly +4 more
doaj +1 more source
Peptide Amphiphiles in Corneal Tissue Engineering [PDF]
Journal of Functional Biomaterials, 2015 The increasing interest in effort towards creating alternative therapies have led to exciting breakthroughs in the attempt to bio-fabricate and engineer live tissues. This has been particularly evident in the development of new approaches applied to reconstruct corneal tissue. The need for tissue-engineered corneas is largely a response to the shortage
Miotto M, Gouveia RM, Connon CJ
openaire +4 more sources
Supramolecular Assembly of Peptide Amphiphiles
Accounts of Chemical Research, 2017 Conspectus Peptide amphiphiles (PAs) are small molecules that contain hydrophobic components covalently conjugated to peptides. In this Account, we describe recent advances involving PAs that consist of a short peptide sequence linked to an aliphatic tail.
Mark P. Hendricks +3 more
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Supramolecular Nanofibers of Peptide Amphiphiles for Medicine [PDF]
Israel Journal of Chemistry, 2013 Abstract Peptide nanostructures are an exciting class of supramolecular systems that can be designed for novel therapies with great potential in advanced medicine. This paper reviews progress on nanostructures based on peptide amphiphiles capable of forming one‐dimensional assemblies that emulate in structure the nanofibers present in
Matthew J, Webber +2 more
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Synthetic, Biologically Active Amphiphilic Peptides [PDF]
Chemistry & Biodiversity, 2007 AbstractAmphiphilic peptides typically consist of a peptide portion that may be 5–25 (or more) amino acids in length. The hydrophobic portion may be a single fatty acid residue, but can also be more elaborate. The main focus of this article lies on the family of synthetic anion binders (SATs) of the general structure (R1)2N‐COCH2OCH2CO‐(Aaa)n‐OR3.
Carl R, Yamnitz, George W, Gokel
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