Results 71 to 80 of about 381,413 (281)

Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species

open access: yesPharmaceuticals, 2015
Candida albicans is the most prevalent cause of fungal infections and treatment is further complicated by the formation of drug resistant biofilms, often on the surfaces of implanted medical devices. In recent years, the incidence of fungal infections by
Namrata Raman   +3 more
doaj   +1 more source

Amphiphilic Cationic β3R3-Peptides: Membrane Active Peptidomimetics and Their Potential as Antimicrobial Agents

open access: yes, 2016
We introduce a novel class of membrane active peptidomimetics, the amphiphilic cationic β3R3-peptides, and evaluate their potential as antimicrobial agents.
Alexander Titz (254988)   +7 more
core   +1 more source

Rational Design of Amphiphilic Fluorinated Peptides: Evaluation of Self-Assembly Properties and Hydrogel Formation [PDF]

open access: yes, 2022
Advanced peptide-based nanomaterials composed of self-assembling peptides (SAPs) gain an emerging interest in pharmaceutical and biomedical applications.
Roland R., Netz   +10 more
core   +2 more sources

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar   +6 more
wiley   +1 more source

Plasma membrane damage limits cytoplasmic delivery by conventional cell penetrating peptides.

open access: yesPLoS ONE
Intracellular delivery of large molecule cargo via cell penetrating peptides (CPPs) is an inefficient process and despite intense efforts in past decades, improvements in efficiency have been marginal. Utilizing a standardized and comparative analysis of
Stéphanie G I Polderdijk   +2 more
doaj   +1 more source

Tuning Secondary Structure and Self-Assembly of Amphiphilic Peptides

open access: yes, 2016
Self-assembly is one of nature's mechanisms by which higher order structures are obtained. Two of the main driving forces for self-assembly, hydrophobic interactions and hydrogen bonding, are both present within amphiphilic peptides.
Joris T. Meijer (2506327)   +3 more
core   +1 more source

Stimuli-responsive amphiphilic peptides for biomedical applications [PDF]

open access: yes, 2016
The overarching goal of the present thesis entitled “Stimuli-Responsive Amphiphilic Peptides for Biomedical Applications” was the de novo design and synthesis of responsive and functional amphiphilic peptides as molecular building blocks to self-assemble
Sigg, Severin J.
core   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

open access: yesAdvanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol   +16 more
wiley   +1 more source

Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. [PDF]

open access: yesPLoS ONE, 2012
Piscidins are antimicrobial peptides (AMPs) that play important roles in helping fish resist pathogenic infections. Through comparisons of tilapia EST clones, the coding sequences of five piscidin-like AMPs (named TP1∼5) of Nile tilapia, Oreochromis ...
Kuan-Chieh Peng   +5 more
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

open access: yesAdvanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

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