Results 31 to 40 of about 95,889 (290)

In-vitro and in-vivo antileishmanial activity of inexpensive Amphotericin B formulations: Heated Amphotericin B and Amphotericin B-loaded microemulsion [PDF]

Experimental Parasitology, 2018
Amphotericin B (AmB) is effective against visceral leishmaniasis (VL), but the renal toxicity of the conventional form, mixed micelles with deoxycholate (M-AmB), is often dose-limiting, while the less toxic lipid-based formulations such as AmBisome® are very expensive.
Rochelle, Andreza, Morais, Vale, Silva, André, Rochelle Do Vale Morais, Andreza, Silva, André Leandro, Cojean, Sandrine, Balaraman, Kaluvu, Bories, Christian, Pomel, Sébastien, Barratt, Gillian, Do Egito, Eryvaldo Sócrates Tabosa, Loiseau, Philippe   +11 more
openaire   +4 more sources

Effects of Several Common Antifungal Drugs (Clotrimazole, Miconazole, Fluconazole) alone and in Combination with Amphotericin B on Candida Species Isolated from Chronic Candidal Vulvovaginitis [PDF]

Journal of Advanced Biomedical Sciences, 2014
Background; Objective: Candidal vulvovaginitis occurs in female genital by the over growth of candida especially candida albicans. This infection may be resistant to therapy and occasionally becomes chronic.
Efate alsadat shojaei, Mehraban Falahati, Faride zaini, Parivash kord bache, Parvaneh rahimi moghadam, Mohammad reza aghamirian, Shima Nozari, Ayesheh Makhdoomi, Sekhavatv ameri, Sanam afshar moghadam   +9 more
doaj   +2 more sources

Using single-dose liposomal amphotericin B for cryptococcal meningitis induction therapy: nurse pearls and practical perspectives [version 2; peer review: 2 approved]

Wellcome Open Research
Background In Uganda where the burden of HIV-associated cryptococcal meningitis is high, conventional amphotericin B deoxycholate has been standard to manage patients with cryptococcal meningitis in research settings.
Richard Kwizera, Cynthia Ahimbisibwe, Jane Frances Ndyetukira, David B. Meya, Carol Namujju   +4 more
doaj   +1 more source

Case report: Reversible encephalopathy associated with liposomal amphotericin B in a patient with cryptococcal meningitis

Frontiers in Neurology, 2022
Liposomal amphotericin B (L-AMB) is an anti-fungus medicine that has fewer side effects than traditional amphotericin B (AMB). Neurotoxicity of L-AMB has rarely been observed, and only one case of leukoencephalopathy during intravenous L-AMB has been ...
Si Luo, Han Wen, Meihong Zhou, Chengsi Wu, Daojun Hong   +4 more
doaj   +1 more source

Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis

Acta Dermato-Venereologica, 2022
The effectiveness of systemic treatment for Leishmania tropica cutaneous leishmaniasis remains unclear. The purpose of the study is to evaluate the efficacy and safety of systemic treatments for L. tropica cutaneous leishmaniasis.
Michal Solomon, Shoshana Greenberger, Maya Milner, Felix Pavlotzky, Aviv Barzilai, Eli Schwartz, Noa Hadayer, Sharon Baum   +7 more
doaj   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source

Protective and antifungal properties of Nanodisk-Amphotericin B over commercially available Amphotericin B

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2017
Objective: Amphotericin B (AMB), a potent antifungal agent, has been employed as topical and systemic therapy for sinonasal fungal infections. A novel formulation of nanodisc (ND) containing super aggregated AMB (ND-AMB) for the treatment of fungal ...
Do-Yeon Cho, Kyle J. Hoffman, Gobind S. Gill, Dong-Jin Lim, Daniel Skinner, Calvin Mackey, Steven M. Rowe, Bradford A. Woodworth   +7 more
doaj   +1 more source

Amphotericin B tissue distribution in autopsy material after treatment with liposomal amphotericin B and amphotericin B colloidal dispersion [PDF]

Journal of Antimicrobial Chemotherapy, 2006
Tissue concentrations of amphotericin B were determined in autopsy material of patients who had been treated with liposomal amphotericin B or amphotericin B colloidal dispersion (colloidal amphotericin B) for suspected or proven invasive fungal infection.Amphotericin B tissue levels were measured in liver, spleen, lung, kidney, and myocardial and brain
Jordan Kountchev, Angela Djanani, Stefan Weiler, Helene Vogelsinger, Romuald Bellmann, Christian J. Wiedermann, Rosa Bellmann-Weiler   +6 more
openaire   +3 more sources

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

Advanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro, María Sancho‐Albero, Silvia Miguel, Andrea Mosseri, Felipe Hornos, Rafael Contreras‐Montoya, Jose L. Hueso, Jesus Santamaria   +7 more
wiley   +1 more source

Amphotericin B Pharmacokinetics in Humans [PDF]

Antimicrobial Agents and Chemotherapy, 1978
The pharmacokinetics of amphotericin B were studied in two patients at the conclusion of long-term therapy for disseminated histoplasmosis. The distribution kinetics of this drug were adequately described by a three-compartment mamillary model with a total distribution volume averaging 4 liters/kg.
Arthur J. Atkinson, John E. Bennett
openaire   +2 more sources