Results 21 to 30 of about 112,937 (259)
Atg8ylation as a general membrane stress and remodeling response
Cell Stress, 2021 The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
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Neuropsychiatric Disease and Treatment, 2023 Zhimin Ding,1,* Jing Gao,2,* Yixuan Feng,1,* Mengyu Wang,1 Huandong Zhao,1 Ruonan Wu,1 Xinyue Zheng,1 Xiaodong Feng,1,2 Mingyin Lai3 1School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou, People’s Republic of ...
Ding Z +8 more
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Journal of Inflammation Research, 2022 Ji Zhu,1,* Hang Chen,2,* Jianan Guo,2 Chen Zha,1 Dezhao Lu2 1The Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, People’s Republic of China; 2School of Life Sciences, Zhejiang ...
Zhu J, Chen H, Guo J, Zha C, Lu D
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NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
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STIM2 interacts with AMPK and regulates calcium‐induced AMPK activation [PDF]
The FASEB Journal, 2018 ABSTRACT AMPK is a crucial regulator of energy homeostasis that acts downstream of its upstream kinase liver kinase B1 (LKB1) and calcium/calmodulin‐dependent protein kinase 2 (CaMKK2). LKB1 primarily phosphorylates AMPK after energy stress, whereas calcium‐mediated activation of AMPK requires CaMKK2, although the
Chauhan, Anoop Singh +7 more
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The Role of AMPK Signaling in Ulcerative Colitis
Drug Design, Development and Therapy, 2023 Yuyi Yuan,1,* Fang Wang,2,* Xingxing Liu,1,* Bo Shuai,1 Heng Fan1 1Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022,
Yuan Y, Wang F, Liu X, Shuai B, Fan H
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Curcumin ameliorates gestational diabetes in mice partly through activating AMPK
Pharmaceutical Biology, 2019 Context: In vitro and in vivo research has shown that curcumin can alleviate diabetes and the relevant complications. Objective: To investigate the effect of curcumin on gestational diabetes (GD).
Xuehong Lu +4 more
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Journal of Applied Animal Research, 2021 Muscle fiber is the basic unit of skeletal muscle. Muscle fiber types play a crucial role in improving meat quality. In the current study, Wistar rats were chronic injected with 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) for four weeks ...
Yanru Hou +7 more
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Innovative therapeutic strategies for cardiovascular disease
EXCLI Journal : Experimental and Clinical Sciences, 2023 As a significant non-communicable disease, cardiovascular disease is the leading cause of death for both men and women, comprises almost twenty percent of deaths in most racial and ethnic groups, can affect greater than twenty-five million individuals ...
Kenneth Maiese
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L-carnitine administration effects on AMPK, APPL1 and PPARγ genes expression in the liver and serum adiponectin levels and HOMA-IR in type 2 diabetes rat model induced by STZ and nicotinamide [PDF]
The Ukrainian Biochemical Journal, 2020 Diabetes is a chronic disease and a public health problem globally. L-Carnitine is synthesized in the liver, promotes fatty acids oxidation and currently is used as a supplement against weight gain.
B. Shahouzehi +2 more
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