Results 91 to 100 of about 232,331 (307)

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

open access: yesAdvanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu   +10 more
wiley   +1 more source

Diverse banana endophytes reveal potential genotype-driven community structure affected by domestication

open access: yesFrontiers in Microbiology
Plant endophytic microbiomes play critical roles in plant health, productivity, and stress tolerance, however, their relationship with host genotype remains poorly understood.
Shiva A. Aghdam, Amanda M. V. Brown
doaj   +1 more source

HSV-1-Based Vectors for Gene Therapy of Neurological Diseases and Brain Tumors: Part II. Vector Systems and Applications

open access: yesNeoplasia: An International Journal for Oncology Research, 1999
Many properties of HSV-1 are especially suitable for using this virus as a vector to treat diseases affecting the central nervous system (CNS), such as Parkinson's disease or malignant gliomas.
Andreas Jacobs   +2 more
doaj   +1 more source

Sequencing bias for amplicon ends.

open access: yes, 2013
Shown are data determined by mapping reads for a representative library (index 2 subsample 3) against EMIRGE-reconstructed16S rRNA sequences. A Proportion of mapped library fragments (y-axis) that begin a given number of bp away from the nearest ...
Kim M. Handley (280139)   +5 more
core   +1 more source

454 amplicon sequencing data and related metadata

open access: yes, 2022
Amplicon sequences of 454 data.
Lorena Grubisic (12089846)
core   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Genes, primers and amplicon characteristics.

open access: yes, 2018
Genes, primers and amplicon characteristics.
Fuchen Yang (5680160)   +8 more
core   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

open access: yesAdvanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li   +9 more
wiley   +1 more source

Primer sequences and amplicon sizes.

open access: yes, 2014
Primer sequences and amplicon sizes.
Seimi Satomi-Kobayashi (633759)   +8 more
core   +1 more source

Primer sequences and their associated amplicon sizes.

open access: yes, 2022
Primer sequences and their associated amplicon sizes.
Vett K. Lloyd (11985441)   +1 more
core   +1 more source

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