Results 21 to 30 of about 3,296 (169)

The pharmacokinetics of amygdalin [PDF]

open access: yesArchives of Toxicology, 1982
Amygdalin (D-mandelonitrile-beta-D-gentiobioside) is a cyanogenic glycoside claimed to show anti-cancer activity, sold under the incorrect name "Laetrile". For a sensible discussion of its alleged activity and its established toxicity it is necessary that its fate in the organism is known. The pharmacokinetics of amygdalin have been investigated in the
Rauws, AG, Olling, M, Timmerman, A
openaire   +3 more sources

Amygdalin may potentiate the effects of lapatinib on SK-BR-3 cancer cell death through increasing Bax expression [PDF]

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2023
Background and Aim: : HER-2 Positive breast cancer is one of the aggressive types of cancer and is resistant to chemotherapy drugs such as lapatinib .Amygdalin is a natural compound found in the seeds of fruits such as apricot, peache, apple and almond ...
Bahman Moradi poodeh
doaj  

Host-microbiome metabolism of a plant toxin in bees

open access: yeseLife, 2022
While foraging for nectar and pollen, bees are exposed to a myriad of xenobiotics, including plant metabolites, which may exert a wide range of effects on their health.
Erick VS Motta   +6 more
doaj   +1 more source

Amygdalin as a chemoprotective agent in co-treatment with cisplatin

open access: yesFrontiers in Pharmacology, 2022
Amygdalin is a naturally occurring glycoside used in traditional Chinese medicine and is known to have anti-cancer properties. Even though the anti-cancer properties of amygdalin are well known, its effect on normal cells has not been thoroughly ...
Panayiota Christodoulou   +9 more
doaj   +1 more source

The Multiple Actions of Amygdalin on Cellular Processes with an Emphasis on Female Reproduction

open access: yesPharmaceuticals, 2021
The present review summarizes the current knowledge on the provenance and properties, metabolism and toxicity, mechanism of action, physiological, and therapeutic roles of amygdalin—a molecule present in the seeds of apricot and other plants—with an ...
Adriana Kolesarova   +2 more
doaj   +1 more source

Onco-immunity and therapeutic application of amygdalin: A review

open access: yesJournal of Oral Biology and Craniofacial Research, 2023
Background: Amygdalin is known as a chemical compound derived from various fruits. The glycosides existing in this plant have been historically utilized as an anticancer agent.
Ahmed Mohammed Alwan   +3 more
doaj   +1 more source

Accumulation Pattern of Amygdalin and Prunasin and Its Correlation with Fruit and Kernel Agronomic Characteristics during Apricot (Prunus armeniaca L.) Kernel Development

open access: yesFoods, 2021
To reveal the accumulation pattern of cyanogenic glycosides (amygdalin and prunasin) in bitter apricot kernels to further understand the metabolic mechanisms underlying differential accumulation during kernel development and ripening and explore the ...
Ping Deng   +7 more
doaj   +1 more source

Interactions Between Ephedra sinica and Prunus armeniaca: From Stereoselectivity to Deamination as a Metabolic Detoxification Mechanism of Amygdalin

open access: yesFrontiers in Pharmacology, 2021
Mahuang–Xingren (MX, Ephedra sinica Stapf-Prunus armeniaca L.) is a classic herb pair used in traditional Chinese medicine. This combined preparation reduces the toxicity of Xingren through the stereoselective metabolism of its main active ingredient ...
Yan Qin   +12 more
doaj   +1 more source

Identification of Sweet/Bitter Traits of Apricot Kernel in Southern Xinjiang Based on GC-MS and Organoleptic Evaluation

open access: yesShipin gongye ke-ji, 2023
In order to identify the sweet and bitter identification indicators of almonds, and provide theoretical basis for almond breeding and deep processing. 88 apricot kernels from southern Xinjiang were used as experimental materials. The content of amygdalin
Yage XING   +5 more
doaj   +1 more source

Effect of Amygdalin on Murine Melanoma Cancer Cell Line and Normal Human Fibroblast Cells [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2023
Background and Objectives: Melanoma is the most aggressive and fatal type of skin cancer caused by the uncontrolled proliferation of melanocytes. The ineffectiveness of existing therapies has encouraged researchers to use herbal medicines. Amygdalin is a
Azam Moslehi   +3 more
doaj  

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