Results 71 to 80 of about 4,165 (205)

Exploring Diverse Glycone Preferences of Aspergillus rutinosidases

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
Rutinosidases from Aspergillus niger (AnRut) and A. oryzae (AoRut) catalyze hydrolysis and transglycosylation with non‐natural glycosides as donors, enabling glycosylation of alcoholic and phenolic acceptors. AnRut exhibits broad glycone promiscuity, while AoRut has a narrower substrate scope.
Jitka Brouzdová   +9 more
wiley   +1 more source

Harnessing Hydrogen Cyanide (HCN): Responsive Chemical Tools for Delivering an Emerging Gasotransmitter

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
HCN is an important biological mediator, joining NO, CO, and H2S as a regulatory gasotransmitter. This report outlines the design, development, and application of responsive, activatable, and tunable HCN donors. In‐solution kinetics and selectivity data, as well as demonstration of HCN delivery in live cell environments, support the effectiveness of ...
Michael D. Pluth
wiley   +2 more sources

Analysis of Amygdalin in Various Matrices Using Electrospray Ionization and Flowing Atmospheric-Pressure Afterglow Mass Spectrometry

open access: yesBiomolecules, 2020
Amygdalin is a natural cyanogenic compound that plants produce in the fight against insects and herbivores. Excessive amounts of amygdalin by animals and humans can potentially lead to fatal intoxication.
Maria Guć   +2 more
doaj   +1 more source

Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis

open access: yeseFood, Volume 7, Issue 3, June 2026.
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng   +5 more
wiley   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao   +4 more
wiley   +1 more source

Amygdalin in antineoplastic medicine and the relevance of nanotechnology [PDF]

open access: yes
Amygdalin is a plant-based cyanogenic glycoside that has been the subject of both scientific interest and controversy for decades. Traditionally used in alternative medicine for its diverse biological activities, including anticancer, where amygdalin has
Billa, Nashiru, Queenie, Fernandes
core   +1 more source

Metabolites of amygdalin under simulated human digestive fluids

open access: yes, 2020
In the present study, degradation of amygdalin in the human digestive fluids and absorption of its metabolites by the human small intestine were evaluated by simulating a gastrointestinal digestion model combined with a human intestinal cell culture ...
심순미
core   +1 more source

Amygdalin blocks bladder cancer cell growth in vitro by diminishing cyclin A and cdk2. [PDF]

open access: yesPLoS ONE, 2014
Amygdalin, a natural compound, has been used by many cancer patients as an alternative approach to treat their illness. However, whether or not this substance truly exerts an anti-tumor effect has never been settled.
Jasmina Makarević   +8 more
doaj   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu   +8 more
wiley   +1 more source

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