Results 21 to 30 of about 11,332,305 (264)

Anti-Aβ autoantibodies in amyloid related imaging abnormalities (ARIA): candidate biomarker for immunotherapy in Alzheimer’s disease and cerebral amyloid angiopathy.

Frontiers in Neurology, 2015
Amyloid Related Imaging Abnormalities (ARIA) represent the major severe side effect of amyloid-beta (Aβ) immunotherapy for Alzheimer’s disease (AD).
Jacopo C. DiFrancesco, Jacopo C. DiFrancesco, Martina eLongoni, Martina eLongoni, Fabrizio ePiazza, Fabrizio ePiazza, Fabrizio ePiazza   +6 more
doaj   +3 more sources

Two cases of Amyloid-Related Imaging Abnormalities (ARIA) following lecanemab treatment for alzheimer’s disease and a literature review [PDF]

BMC Neurology
Objective To investigate the imaging characteristics and management strategies of amyloid-related imaging abnormalities (ARIA) in Alzheimer’s disease (AD) patients treated with lecanemab.
Yingte Wang, Qun Yu, Bin Chen, Jing Zhou, Zhiming Li, Wang Liao, Jun Liu, Airong Yang   +7 more
doaj   +2 more sources

Amyloid-Related Imaging Abnormalities (ARIA) in Alzheimer's Disease. [PDF]

Dtsch Arztebl Int
Vöglein J, Levin J, Brendel M.
europepmc   +2 more sources

Safety, tolerability, immunogenicity, and efficacy of UB-311 in participants with mild Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 2a studyResearch in context

EBioMedicine, 2023
Summary: Background: Anti-amyloid vaccines may offer a convenient, affordable, and accessible means of preventing and treating Alzheimer's disease. UB-311 is an anti–amyloid-β active immunotherapeutic vaccine shown to be well-tolerated and to have a ...
Hui Jing Yu, Samuel P. Dickson, Pei-Ning Wang, Ming-Jang Chiu, Chin-Chang Huang, Chiung-Chih Chang, Hope Liu, Suzanne B. Hendrix, Jean-Cosme Dodart, Ajay Verma, Chang Yi Wang, Jeffrey Cummings   +11 more
doaj   +1 more source

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study [PDF]

, 2021
To investigate the natural history and outcomes following treatment for spontaneous amyloid-related imaging abnormalities (ARIA)-like in cerebral amyloid angiopathy-related inflammation (CAA-ri)
Pascarella, Rosario, Masafumi Ihara, Perini, Giulia, Shima, Atsushi, Ricardo Nitrini, Roberto Marconi, Maria Sessa, Laura Antolini, Domenico Inzitari, Rosario Pascarella, Valenti, Raffaella, Gianpaolo Basso, Di Lazzaro, Vincenzo, Alessia Giossi, Charidimou, Andreas, Andreas Charidimou, Marcon, Michela, Roxana O. Carare, Andrea Arighi, Carare, Roxana, Tagliavini, Fabrizio, Elio Scarpini, and Fabrizio Piazza, Jacopo C. DiFrancesco, Mario Cirillo, Hagiwara, Yuta, Zedde, Marialuisa, Raffaella Valenti, Fabrizio Tagliavini, Berardino Orlandi, Villarejo-Galende, Alberto, Carare, Roxana O, Carlo Ferrarese, Vincenzo Di Lazzaro, Marialuisa Zedde, Sessa, Maria, Inzitari, Domenico, Arighi, Andrea, Basso, Gianpaolo, Marconi, Roberto, Nitrini, Ricardo, Cirillo, Mario, Michela Marcon, Ziliotto, Nicole, Alessandro Padovani, Alberto Villarejo-Galende, Yuta Hagiwara, Scarpini, Elio, Massimo Caulo, Francesco Perini, Piazza, Fabrizio, Cagnin, Annachiara, Caulo, Massimo, Juan Francisco Vazquez-Costa, Nicole Ziliotto, Antolini, Laura, Vázquez-Costa, Juan Francisco, Ferrarese, Carlo, Padovani, Alessandro, Ihara, Masafumi, Perini, Francesco, Atsushi Shima, DiFrancesco, Jacopo C, Annachiara Cagnin, Giossi, Alessia, Giulia Perini, Orlandi, Berardino, Ziliotto N., Caulo M., Scarpini E., Charidimou A., Marcon M., Marconi R., Carare R. O., Piazza F., Padovani A., Sessa M., Tagliavini F., Orlandi B., Arighi A., Perini F., Basso G., Giossi A., Cirillo M., Villarejo-Galende A., Cagnin A., Di Lazzaro V., Valenti R., Antolini L., Ferrarese C., Pascarella R., Nitrini R., DiFrancesco J. C., Shima A., Ihara M., Hagiwara Y., Perini G., Zedde M., Vazquez-Costa J. F., Inzitari D., Fabrizio Piazza   +100 more
core   +1 more source

Aducanumab-Related Amyloid-Related Imaging Abnormalities

Clinical Nuclear Medicine, 2022
Abstract When the FDA granted accelerated approval of Biogen's Alzheimer disease drug, aducanumab (marketed as Aduhelm), it deviated from its mission of guaranteeing drug safety and efficacy because the approval was based exclusively on a perceived dose-dependent reduction in brain amyloid deposits and not upon a proven clinical effect.
Høilund-Carlsen, Poul F., Werner, Thomas J., Alavi, Abass, Revheim, Mona Elisabeth   +3 more
openaire   +3 more sources

MR Imaging Features of Amyloid-Related Imaging Abnormalities [PDF]

American Journal of Neuroradiology, 2013
AD is one of the few leading causes of death without a disease-modifying drug; however, hopeful agents are in various phases of development. MR imaging abnormalities, collectively referred to as amyloid-related imaging abnormalities, have been reported for several agents that target cerebral Aβ burden.
J, Barakos, R, Sperling, S, Salloway, C, Jack, A, Gass, J B, Fiebach, D, Tampieri, D, Melançon, Y, Miaux, G, Rippon, R, Black, Y, Lu, H R, Brashear, H M, Arrighi, K A, Morris, M, Grundman   +15 more
openaire   +2 more sources

Subcortical signal alteration of corticospinal tracts. A radiologic manifestation of ARIA: A case report

Radiology Case Reports, 2023
Patients with Alzheimer's disease who have been given monoclonal antibodies targeting amyloid-β (Aβ) (eg, gantenerumab, donanemab, lecanemab, and aducanumab) for scientific purposes may have a spectrum of imaging findings known as amyloid-related imaging
Houman Sotoudeh, MD, Mohammadreza Alizadeh, MD, Ramin Shahidi, MD, Parnian Shobeiri, MD, MPH, Natelson love, MD, Aparna Singhal, MD   +5 more
doaj   +1 more source

Cerebral Amyloid Angiopathy: Emerging Concepts [PDF]

Journal of Stroke, 2015
Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved.
Masahito Yamada
doaj   +1 more source

Amyloid and tau PET in cerebral amyloid angiopathy-related inflammation two case reports and literature review

Frontiers in Neurology, 2023
BackgroundCerebral amyloid angiopathy-related inflammation (CAA-ri) is a clinical syndrome characterized by MRI findings of amyloid-related imaging abnormalities-edema (ARIA-E) suggestive of autoimmune and inflammatory reaction and hemorrhagic evidence ...
Jhih-Yong Yang, Yung-Tsai Chu, Hsin-Hsi Tsai, Hsin-Hsi Tsai, Jiann-Shing Jeng   +4 more
doaj   +1 more source