Results 91 to 100 of about 76,126 (160)

NMR studies of the amyloid beta-peptide

, 2007
The Amyloid beta peptide (Ab) is related to Alzheimer’s disease and is suggested to be the molecular pathogenic species of the disease, probably through the neurotoxic effect of Ab oligomers. Here the results from biophysical studies of Ab and fragments thereof, are presented.
openaire   +1 more source

Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane. [PDF]

Neurobiol Dis, 2018
Zhang L, Trushin S, Christensen TA, Tripathi U, Hong C, Geroux RE, Howell KG, Poduslo JF, Trushina E.   +8 more
europepmc   +1 more source

Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides. [PDF]

Front Aging Neurosci, 2017
Yang S, Pascual-Guiral S, Ponce R, Giménez-Llort L, Baltrons MA, Arancio O, Palacio JR, Clos VM, Yuste VJ, Bayascas JR.   +9 more
europepmc   +1 more source

The Kinetics and Thermodynamics of the Amyloid Beta Peptide

Amyloids are a category of protein structures where many individual polypeptide chains fold to form long β-sheet fibrils. These are strongly associated to many of today's incurableand fatal diseases, such as Alzheimer's and Parkinson's disease. However, the exact cause of toxicity and disease initiation remains elusive.
openaire   +1 more source

Differential A-to-I editing of SINE B2 RNAs unveils an epitranscriptome response to Aβ neurotoxicity. [PDF]

Life Sci Alliance
Mitchell L, Saville L, Gollen B, Haight T, Roy R, Turner C, Cheng Y, Kovalchuk I, Mohajerani MH, Zovoilis A.   +9 more
europepmc   +1 more source

Predicting Peptide Aggregation with Protein Language Model Embeddings. [PDF]

J Chem Inf Model
Eschbach E, Deibler K, Korani D, Swanson S.   +3 more
europepmc   +1 more source

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source

The Monomeric Conformational Ensembles of Aβ40 and Aβ42 Encode Their Differential Amyloid Aggregation Propensity. [PDF]

J Phys Chem B
Cadenelli I, Ciccolo A, Tagliabue A, Rossi G, Conti Nibali V, Bochicchio D.   +5 more
europepmc   +1 more source