Results 221 to 230 of about 118,464 (350)

Real‐world effectiveness of targeted therapies in ATTR cardiomyopathy: A meta‐analysis integrating population‐based data

open access: yesESC Heart Failure, EarlyView.
Summary of the meta‐analysis evaluating the effectiveness of targeted therapies for transthyretin amyloid cardiomyopathy (ATTR‐CM). Pooled data from 10 studies (n = 5203) showed a 39% relative reduction in all‐cause mortality (RR: 0.61, 95% CI: 0.52–0.70).
Alexios S. Antonopoulos   +5 more
wiley   +1 more source

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, EarlyView.
The diagnosis of atrial cardiomyopathy (AtCM) requires electrical atrial dysfunction, with evidence of either mechanical atrial dysfunction, atrial enlargement, or excessive atrial fibrosis. The diagnostic cut‐points presented are for standard electrocardiogram and echocardiogram studies (see Figure 1 for further detail).
Jerremy Weerts   +26 more
wiley   +1 more source

Beta amyloid peptides accumulation induces the over expression of TSPO translocator in optic nerve, visual cortex and in the retina in Alzheimer s disease and aging model

open access: green, 2017
Luis F Hernandez   +8 more
openalex   +1 more source

Clinical phenotype and prognosis of real‐world patients with wild‐type transthyretin amyloid cardiomyopathy treated with tafamidis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Aims Tafamidis reshaped the treatment paradigm in transthyretin amyloid cardiomyopathy (ATTR‐CM) based on a phase‐3 randomized controlled trial, but real‐world data on its use remain limited. This study aimed to assess in a large, contemporary, real‐world cohort of patients with wild‐type ATTR‐CM (ATTRwt‐CM) (i) the clinical phenotype of patients ...
Aldostefano Porcari   +48 more
wiley   +1 more source

Artificial intelligence‐based echocardiographic assessment for monitoring disease progression in transthyretin cardiac amyloidosis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Artificial intelligence (AI)‐based estimation of stroke volume for risk prediction in amyloid transthyretin cardiomyopathy (ATTR‐CM). ATTRv, hereditary transthyretin amyloidosis; ATTRwt, wild‐type transthyretin amyloidosis; CI, confidence interval; HR, hazard ratio; IQR, interquartile range; LVOT‐VTI, left ventricular outflow tract velocity‐time ...
Lucia Venneri   +23 more
wiley   +1 more source

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