Results 221 to 230 of about 1,185,249 (285)

Differential A-to-I editing of SINE B2 RNAs unveils an epitranscriptome response to Aβ neurotoxicity. [PDF]

Life Sci Alliance
Mitchell L, Saville L, Gollen B, Haight T, Roy R, Turner C, Cheng Y, Kovalchuk I, Mohajerani MH, Zovoilis A.   +9 more
europepmc   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, EarlyView.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Quantifying the Diamagnetic and Paramagnetic Components of Beta-Amyloid Plaques Using Decomposed Quantitative Susceptibility Mapping in Mouse Models of Alzheimer's Disease. [PDF]

NMR Biomed
Liu J, Chen J, Wyatt-Johnson SK, Chen J, Liu Z, Wu H, Feng L, Brutkiewicz RR, Wang N.   +8 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Aggregation of Amyloid-like Peptides in Different Solvents. [PDF]

J Mol Liq
Sungted S, Rangubpit W, Phongphanphanee S, Yoshida N, Dias CL, Wong-Ekkabut J.   +5 more
europepmc   +1 more source

Targeting protein aggregate co-pathologies in neurodegeneration: a viable therapeutic strategy? [PDF]

Mol Neurodegener Adv
Buck SA, Madhavan SS, Sanders LH.
europepmc   +1 more source

Association between Alzheimer's disease and MHC-I antigen processing and presentation pathway: a narrative review. [PDF]

Front Immunol
Wang C, Yun Q, Zhang Z, Zhao H, Lin F, Cao H.   +5 more
europepmc   +1 more source

Beyond β-amyloid: transthyretin cerebral amyloid angiopathy. [PDF]

Neurol Sci
Vera-Cáceres C, Romanini CM, Platas MG, Sánchez-Miranda Román I, Traba AL, Aguilera Y, Díaz AD, Hernández AP, Acosta BB, Chi D.   +9 more
europepmc   +1 more source

Alzheimer's Disease: From Molecular Pathogenesis to Disease-Modifying Therapies and Clinical Implementation in Aging Populations. [PDF]

Clin Interv Aging
Zrineh A, Akwan R, Darawsheh R, Nasser A, Elsharkawy MM.   +4 more
europepmc   +1 more source

Analytical framing of Amyloid beta monoclonal antibody trials in Alzheimer's disease can obscure clinical effects. [PDF]

Alzheimers Dement
Tijms BM, van Harten AC, Carillo MC, Scheltens P, Vijverberg EGB.   +4 more
europepmc   +1 more source