Results 241 to 250 of about 118,464 (350)

Plasmonics‐Enhanced Characterization of Cervid PrP (87–114) Fragment Aggregates in Solution

Journal of Biophotonics, EarlyView.
Multimodal nanophotonics platform combining plasmon‐enhanced imaging, label‐free SERS, and optical staining reveals new insights into the aggregation of the cervid PrP (87–114) fragment, an amyloidogenic sequence linked to chronic wasting disease susceptibility.
Shinki Midha, Aishwarya Sriraman, Lyudmyla Dorosh, Holger Wille, Maria Stepanova   +4 more
wiley   +1 more source

Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels. [PDF]

Neuron, 2017
Zhao Y, Sivaji S, Chiang MC, Ali H, Zukowski M, Ali S, Kennedy B, Sklyar A, Cheng A, Guo Z, Reed AK, Kodali R, Borowski J, Frost G, Beukema P, Wills ZP.   +15 more
europepmc   +1 more source

A Phase 1 Study of the Pharmacokinetics, Safety, and Tolerability of Posdinemab (JNJ‐63733657) in Healthy Chinese Adults

The Journal of Clinical Pharmacology, EarlyView.
Abstract Posdinemab, a humanized immunoglobulin G1/κ monoclonal antibody, binds with high affinity to phosphorylated tau protein which is associated with Alzheimer's disease (AD) pathophysiology. Posdinemab reduced tau seeding in murine models and was well tolerated in Phase‐1 clinical studies.
Fangfang Wang, Juanfang Liu, Daisy Bai, Lingjue Li, Maggie Fedgchin, David Henley, Haiyan Li, Fan Zhang   +7 more
wiley   +1 more source

Expedient Access to Gold/Quantum‐Dot Nanohybrids Mediated by Poly(ethylene Glycol) Ligands of Distinct Macromolecular Architecture

Macromolecular Rapid Communications, EarlyView.
We demonstrate that distinct quantum dots with ZnS shells can be incorporated directly into poly(ethylene glycol) brushes at gold nanoparticle surfaces, based on non‐covalent interactions between the quantum‐dot surface and PEG monomer. The structure and photoluminescence properties of obtained gold/quantum‐dot conjugates can be engineered by adjusting
Olga V. Kuharenko, Artsiom Antanovich, Avijit Saha, Aliaksei Ivanchanka, Martin Müller, Vladimir Lesnyak, Annette Kraegeloh, Christian Rossner   +7 more
wiley   +1 more source

The effect of cognitive-motor dual-task training on cognitive function and plasma amyloid .BETA. peptide 42/40 ratio in healthy elderly persons

, 2017
Yokoyama Hisayo, Emiko Morita, Imai Daiki, Naghavi Nooshin, Takeda Ryosuke, Akemi Ota, Kawai Eriko, Genta Hanno, Okazaki Kazunobu   +8 more
openalex   +1 more source

Correction: Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity

, 2016
Stephan Rudolph, Antonia Klein, Markus Tusche, Christine Schlosser, Anne Elfgen, Oleksandr Brener, Charlotte E. Teunissen, Lothar Gremer, Susanne Aileen Funke, Janine Kutzsche, Dieter Willbold   +10 more
openalex   +2 more sources

Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions

, 2020
Liting Deng, Paul A. Haynes, Yunqi Wu, Ardeshir Amirkhani, Karthik Shantharam Kamath, Jemma Wu, Kanishka Pushpitha, Veer Bala Gupta, Stuart L. Graham, Vivek Gupta, Mehdi Mirzaei   +10 more
openalex   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Impact of long-term Zn supplementation in liver tissue of APP/PS1 mice: A pilot study attending to essential metals, metalloproteins and amyloid beta 42 peptide

Lobo Lara
openalex   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source