Results 201 to 210 of about 94,035 (378)
ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack+4 more
wiley +1 more source
Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley +1 more source
Beta-Amyloid Precursor Protein Staining in Nonhomicidal Pediatric Medicolegal Autopsies
R. Ross Reichard+3 more
openalex +1 more source
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley +1 more source
Protease nexin-2/amyloid beta-protein precursor: a cerebral anticoagulant? [PDF]
openaire +2 more sources
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi+2 more
wiley +1 more source
Relation of the Amyloid β Protein Precursor to Heparan Sulfate Proteoglycans [PDF]
RU Margolis+5 more
openaire +3 more sources
Abstract Recently, ion mobility spectrometry‐mass spectrometry (IMS‐MS) has become more readily incorporated into various omics‐based workflows. These growing applications are due to developments in instrumentation within the last decade that have enabled higher‐resolution ion mobility separations.
Cameron N. Naylor, Gabe Nagy
wiley +1 more source
Identification of fibrinogen Aα-chain as an amyloid precursor protein in a case of canine coronary artery amyloidosis. [PDF]
Iwaide S+9 more
europepmc +1 more source