BMEMat, EarlyView.LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng +4 more
wiley +1 more source
Analytical framing of Amyloid beta monoclonal antibody trials in Alzheimer's disease can obscure clinical effects. [PDF]
Alzheimers DementTijms BM +4 more
europepmc +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Fisetin Attenuates Amyloid-Beta-Induced Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells: Integrating In Silico Target Prediction and In Vitro Validation. [PDF]
J Biochem Mol ToxicolJaiswal C, Singh I, Singh AK.
europepmc +1 more source
BMEMat, EarlyView.Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu +10 more
wiley +1 more source
Theranostic Nanoparticles for Fluorosensitive Visualization and Inhibition of Amyloid Beta-Induced Neuroinflammation. [PDF]
Part Part Syst CharactTamima U +9 more
europepmc +1 more source
Raman Optical Activity as a Tool to Monitor Polynucleotide Conformation in Solutions
Chemistry – A European Journal, EarlyView.Raman optical activity (ROA) studies of nucleic acids have been hindered by limited computational tools to link the spectra to the structure. The study shows that accurate density functional simulations are possible for model nucleotides, bringing more information about molecular geometry and dynamics in solutions.
Mohammed Siddhique Para Kkadan +5 more
wiley +1 more source
Potential correlation between chronic pain and amyloid beta in Alzheimer's disease. [PDF]
Front Pain Res (Lausanne)Liu Y, Wang XP.
europepmc +1 more source
Fibrilpaint: A Class of Amyloid‐Targeting Peptides
Chemistry – A European Journal, EarlyView.FibrilPaints are modular peptides engineered to recognize amyloid fibrils. By systematically varying charge, sequence, and termini, their binding behavior can be tuned while retaining recognition. Successful binding ″paints″ fibrils for visualization and opens routes toward targeted degradation and diagnostic applications.
Júlia Aragonès Pedrola +8 more
wiley +1 more source
Elucidating the neuropathological and molecular heterogeneity of amyloid beta and tau in Alzheimer's disease through machine learning and transcriptomic integration. [PDF]
Alzheimers DementZhao K +10 more
europepmc +1 more source