Results 231 to 240 of about 1,464,719 (336)

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

Silk fibroin‐based biomaterials for spinal cord injury repair: Recent advances and future prospects

BMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of silk fibroin‐based biomaterials in spinal cord injury repair, focusing on environmentally friendly processing techniques, and the strategies for designing composite scaffolds as well as discussing the advantages and current challenges of silk fibroin‐based biomaterials in spinal ...
Xiaoliang Cui, Xuanwen Wang, Siying Liu, Lilei Wang, Menghong Li, Jun Zhang, Li Wang, Ke‐Qin Zhang   +7 more
wiley   +1 more source

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

BMEMat, EarlyView.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad, Wan Nurhidayah Wan Hanaffi, Anas Islam, Aimen Salman, Mohd Muazzam Khan, Faiyaz Shakeel, Qiang Cai, Xiaojun Cai, Quazi T. H. Shubhra   +8 more
wiley   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Recent Insights Into Alzheimer's Disease: Advances in Pathophysiology and Therapeutic Strategies

Brain Health, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a complex neurodegenerative disorder driven by interplay among amyloid‐β (Aβ) plaques, tau neurofibrillary tangles, inflammation and comorbid pathologies. Recent advances in biomarkers and therapeutic approvals have reshaped our understanding of its pathophysiology and treatment landscape.
Jiong Shi, Jeffery Cummings, Jacques Touchon, Bruno Vellas   +3 more
wiley   +1 more source

Chemical and Biological Properties of Hymenaea courbaril L.: A Review

Chemistry &Biodiversity, EarlyView.
PRISMA‐style flowchart showing the screening process of studies identified and selected in the review has been added to the attachments. ABSTRACT Hymenaea courbaril L., commonly known as jatobá, is a plant traditionally used by native populations for medicinal purposes, in addition to providing edible fruits and durable wood for construction.
Cicera Alane Coelho Gonçalves, Geane Gabriele de Oliveira Souza, Ana Maria Fernandes Duarte, Joice Barbosa do Nascimento, Fázia Fernandes Galvão Rodrigues, José Galberto Martins da Costa, Fabíola Fernandes Galvão Rodrigues   +6 more
wiley   +1 more source

Sequence‐Dependent Heterotypic Assemblies of Intrinsically Disordered Peptides

ChemistryEurope, EarlyView.
Two oppositely charged intrinsically disordered peptides (IDPs) coassemble into heterotypic nanofibers. Homochiral mixtures (L/L IDPs) form homogeneous, aligned bundles with the more positive IDP. Heterochiral mixtures (L/D IDPs) yield heterogeneous, twisted bundles as positive‐IDP content increases.
Yuchen Qiao, Matthew Chu, Grace Wu, Zhiyu Liu, Bing Xu   +4 more
wiley   +1 more source