Results 241 to 250 of about 249,317 (377)

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

open access: yesAnimal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao   +12 more
wiley   +1 more source

Interactions of memantine and rivastigmine with graphene oxide nanocarrier and beta-amyloid protein using molecular docking and in-silico methods

open access: yesHeliyon
Alzheimer's disease is characterized by the accumulation of beta-amyloid plaques and neurofibrillary tangles. Effective therapeutic strategies involve inhibiting the formation of beta-amyloid aggregates and destabilizing existing ones.
Fateme Davoudi   +2 more
doaj  

Older Amyloid Beta as a Candidate Blood Biomarker of Early Cognitive Decline in the Elderly-A Preliminary Study. [PDF]

open access: yesCurr Issues Mol Biol
McFarlane O   +4 more
europepmc   +1 more source

Framework for assessing the risk to a field from fraudulent researchers: A case study of Alzheimer's disease

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Concerns over research integrity are rising, with increasing attention to potential threats from untrustworthy authors. We established a framework to gauge the potential negative influence of researchers potentially engaged in misconduct. The field of Alzheimer's disease (AD) research has been a focal point of these worries. This study aims to
Chaoqun Ni, B. Ian Hutchins
wiley   +1 more source

Amyloid Beta-Induced Neuronal Death is Bax-Dependent but Caspase-Independent [PDF]

open access: bronze, 2000
Lee A. Selznick   +4 more
openalex   +1 more source

Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases

open access: yesBioEssays, EarlyView.
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley   +1 more source

An approach to predict and inhibit Amyloid Beta dimerization pattern in Alzheimer's disease. [PDF]

open access: yesToxicol Rep
Roy S   +6 more
europepmc   +1 more source

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