Results 281 to 290 of about 249,317 (377)

Effect of amyloid beta peptide on poly(ADP-ribose) polymerase activity in adult and aged rat hippocampus.

, 2000
Joanna B. Strosznajder, Henryk Jęśko, Robert P. Strosznajder   +2 more
openalex   +2 more sources

Deferasirox Derivatives as Inhibitors of Kallikrein‐Related Peptidases Associated to Neurodegenerative Diseases

ChemMedChem, EarlyView.
Dysregulated proteolysis mediated by kallikrein‐related peptidases (KLKs) and iron overload are involved in the progression of neurodegenerative diseases. Deferasirox, an clinically‐approved iron chelator, and its newly synthesized derivatives have been identified as inhibitors of major central nervous system KLKs with low cytotoxicity and effective ...
Rilès Boumali, Elodie David, Nancy Chaaya, Morane Lucas, Sabrina Aït Amiri, Valérie Lefort, Anthony Nina‐Diogo, Michèle Salmain, Isabelle Petropoulos, Vincent Corcé, Chahrazade El Amri, Candice Botuha   +11 more
wiley   +1 more source

Sub-Immunosuppressive Tacrolimus Ameliorates Amyloid-Beta and Tau Pathology in 3xTg-AD Mice. [PDF]

Int J Mol Sci
Silva J, Tumurbaatar B, Guptarak J, Zhang WR, Fracassi A, Taglialatela G.   +5 more
europepmc   +1 more source

Early histopathological changes in CA1 neurons by co-injection of beta-amyloid (Aβ) with ibotenate into rat hippocampus

, 2000
Seiko Nagata, Kiyoshi Morimoto, Isao Kaneko   +2 more
openalex   +1 more source

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons.

, 1996
Éric Paradis, Hélène Douillard, Maria Koutroumanis, Cynthia G. Goodyer, Andréa C. LeBlanc   +4 more
openalex  

Magnetic Fields, Melatonin, and Amyloid Beta Protein in Electric Utility Workers

, 2000

openalex   +1 more source

Transthyretin amyloid cardiomyopathy in aortic stenosis patients scheduled for transcatheter aortic valve implantation

ESC Heart Failure, EarlyView.
Abbreviations: TAVI, transcatheter aortic valve implantation; ATTR‐CM, transthyretin cardiac amyloidosis. We aimed to diagnose occult ATTR‐CM in patients with severe aortic stenosis undergoing TAVI using bone scintigraphy. We verified a diagnosis of ATTR‐CM in 8 of 171 (4.7 %) consecutive aortic stenosis patients who underwent TAVI.
Margrethe Flesvig Holt, August Flø, Esra Kaya, Sophie Foss Kløve, Hege Martinsen, Kristine Amlie, Petter Storsten, Thomas Misje Mathiisen, Kristoffer Russell, Christian Hesbø Eek, Helge Skulstad, Melinda Raki, Lars Gullestad, Anders Hodt, Einar Gude, Kaspar Broch   +15 more
wiley   +1 more source

Molecular Simulation of the Binding of Amyloid Beta to Apolipoprotein A-I in High-Density Lipoproteins. [PDF]

Int J Mol Sci
Malajczuk CJ, Mancera RL.
europepmc   +1 more source