Results 291 to 300 of about 249,317 (377)

Amyloid beta protein affects poly(ADP-ribose) polymerase activity in PC-12 cells in culture

, 2000
Robert Banasik
openalex   +2 more sources

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem, Teresa C. Leone, Christopher Petucci, Clarissa Shoffler, Ravindra C. Kodihalli, Tiffany Hidalgo, Cheryl Tow‐Keogh, Jessica Mancuso, Iphigenia Tzameli, Donald Bennett, John D. Groarke, Rachel J. Roth Flach, Daniel J. Rader, Daniel P. Kelly   +13 more
wiley   +1 more source

Small-Molecule Inhibitors of Amyloid Beta: Insights from Molecular Dynamics-Part A: Endogenous Compounds and Repurposed Drugs. [PDF]

Pharmaceuticals (Basel)
Atanasova M.
europepmc   +1 more source

Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics

ESC Heart Failure, EarlyView.
Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti, Ghaith Sharaf Dabbagh, Fabrizio Ricci, Sabina Gallina, Roberta Giansante, Ron Jacob, Edmond Obeng‐Gyimah, Leslie T. Cooper Jr, Sanjay K. Prasad, David H. Birnie, Andrew P. Landstrom, Selma F. Mohammed, Saidi Mohiddin, Mohammed Y. Khanji, Anwar A. Chahal   +14 more
wiley   +1 more source

Misfolded amyloid-beta conformational variants (strains) as drivers of Alzheimer's disease neuropathology. [PDF]

Neural Regen Res
Saieva S, Morales R.
europepmc   +1 more source

Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells.

, 1997
Tsuneo Yamazaki, Edward H. Koo, Dennis J. Selkoe   +2 more
openalex  

Role of a tyrosine residue in metal-induced aggregation of the amyloid beta-peptide

, 2001
T. Miura, Kenta Suzuki, Hideyuki Takeuchi   +2 more
openalex   +2 more sources

Microglia degrade Alzheimer's amyloid-beta deposits extracellularly via digestive exophagy. [PDF]

Cell Rep
Jacquet RG, González Ibáñez F, Picard K, Funes L, Khakpour M, Gouras GK, Tremblay MÈ, Maxfield FR, Solé-Domènech S.   +8 more
europepmc   +1 more source

Skeletal muscle and subcutaneous fat quantity as prognostic indicators in cardiac amyloidosis

European Journal of Heart Failure, EarlyView.
Aims Disease‐related changes in body composition are associated with worse outcomes in chronic heart failure. In cardiac amyloidosis (CA), the prognostic value of direct body composition measures is understudied. Methods and results We identified 160 consecutive patients with CA (transthyretin [ATTR] or light chain [AL]) diagnosed between 2001 and 2021
Joshua Longinow, Saeid Mirzai, Po‐Hao Chen, Mazen Hanna, W.H. Wilson Tang   +4 more
wiley   +1 more source