Results 121 to 130 of about 82,488 (290)

New capacities of the diagnosis and monitoring of the course of AL-amyloidosis

Терапевтический архив, 2010
Aim: to define the clinical value of various concentrations of immunoglobulin light chains (ILCs) in patients with AL amyloidosis. Subjects and methods.
V V Rameyev, L V Kozlovskaya, I N Kogarko, B S Kogarko   +3 more
doaj  

Evidence for a nonsecretory, acidic degradation pathway for amyloid precursor protein in 293 cells. Identification of a novel, 22-kDa, beta-peptide-containing intermediate.

, 1992
Jeroen Knops, Ivan Lieberburg, Sukanto Sinha   +2 more
openalex   +1 more source

Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein. [PDF]

, 1995
Paula M. Moran, Linda S. Higgins, Barbara Cordell, Paul Moser   +3 more
openalex   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha.

, 1993
Barbara E. Slack, Roger M. Nitsch, Etta Livneh, George M. Kunz, Jeff Breu, Hagit Eldar-Finkelman, R. J. Wurtman   +6 more
openalex   +1 more source

The secreted form of the Alzheimer's β-amyloid precursor protein stimulates a membrane-associated guanylate cyclase [PDF]

, 1995
Steven W. Barger, Mark P. Mattson
openalex   +1 more source

Magnetocardiography for the non‐invasive diagnosis of myocardial inflammation in cardiac amyloidosis: A proof‐of‐concept study

ESC Heart Failure, EarlyView.
Abstract Aims Myocardial inflammation is increasingly recognized for its association with impaired clinical outcomes in cardiac amyloidosis but a trend towards less invasive diagnosis impedes its detection. The aim of this study was to assess magnetocardiography (MCG) as a potential non‐invasive method to diagnose myocardial inflammation in patients ...
Maximilian Leo Müller, Phillip Suwalski, Finn Wilke, Ekaterina Latinova, Gamze Satilmis, Nicolas Musigk, Anna Brand, Isabel Mattig, Fabian Knebel, Daniel Messroghli, Katrin Hahn, Sebastian Spethmann, Ulf Landmesser, Bettina Heidecker   +13 more
wiley   +1 more source

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
The diagnosis of atrial cardiomyopathy (AtCM) requires electrical atrial dysfunction, with evidence of either mechanical atrial dysfunction, atrial enlargement, or excessive atrial fibrosis. The diagnostic cut‐points presented are for standard electrocardiogram and echocardiogram studies (see Figure 1 for further detail).
Jerremy Weerts, Otilia Țica, Julia Aranyo, Christian Basile, Angelina Borizanova‐Petkova, Josip Andjelo Borovac, Massimiliano Camilli, Martin Eichenlaub, Emiliano Fiori, Tim Van Loon, Coenraad Withaar, Diana Zakarkaitė, Matthias D. Zink, Marianna Adamo, Alberto Aimo, Elena Arbelo, Felipe Bisbal Van Bylen, Dimitrios T. Farmakis, Dobromir Dobrev, Jelena Čelutkienė, Michael Böhm, Andrew Coats, Marco Metra, Giuseppe Rosano, Frank Ruschitzka, Antoni Bayes‐Genis, Dipak Kotecha   +26 more
wiley   +1 more source

Alzheimer's amyloid precursor protein produced by recombinant baculovirus expression. Proteolytic processing and protease inhibitory properties.

, 1991
David E. Lowery, J. M. Pasternack, P. A. Gonzalez-DeWhitt, Heidi A. Zürcher-Neely, Che‐Shen C. Tomich, Richard Altman, Michael B. Fairbanks, Robert L. Heinrikson, Steven G. Younkin, Barry Greenberg   +9 more
openalex   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source