Results 131 to 140 of about 82,488 (290)

Regulation of β-Amyloid Secretion by FE65, an Amyloid Protein Precursor-binding Protein [PDF]

, 1999
Shasta L. Sabo, Lorene M. Lanier, Annat Ikin, Olga Khorkova, Sudhir Sahasrabudhe, Paul Greengard, Joseph D. Buxbaum   +6 more
openalex   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Oxidative Assemblies of Flavonoids (Quercetin, Morin) to Form Dimer in Weak Base Circumstances and Its Mechanism Analysis by UPLC‐ESI‐TSQ‐MS/MS

Food Chemistry International, EarlyView.
Product identification of flavonoids under weak base conditions and mechanism analysis of dimer formation by the oxidative assembly of quercetin and morin, respectively. ABSTRACT Flavonoids are susceptible to autoxidation in aqueous solutions, which is largely dependent on pH, generating various free radicals and oxidation products. Quercetin and morin
Pengren Zou, Susan Jyakhwo, Paz Otero, Shengxiong Chen, Celia Costas, Carla Cameselle, Fan Zhang, Hui Cao   +7 more
wiley   +1 more source

Conversion of the Alzheimer's beta-amyloid precursor protein (APP) Kunitz domain into a potent human neutrophil elastase inhibitor.

, 1991
Sukanto Sinha, Jeroen Knops, Frederick Esch, Elizabeth D. Moyer, Tilman Oltersdorf   +4 more
openalex   +1 more source

Prostaglandin E₂Stimulates Amyloid Precursor Protein Gene Expression: Inhibition by Immunosuppressants [PDF]

, 1999
Robert K. K. Lee, Stefan Knapp, Richard J. Wurtman   +2 more
openalex   +1 more source

Building Immunocompetent Cerebral Organoids From a Developmental Perspective

Glia, EarlyView.
Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statistical analysis to help develop standardized protocols. ABSTRACT Cerebral organoids derived from human induced pluripotent stem cells (iPSCs) are increasingly ...
Xabier Cuesta‐Puente, Marco Gonzalez‐Dominguez, Marta Pereira‐Iglesias, Nerea Perez‐Arriazu, Patricia Villegas‐Zafra, Paula Ramos‐Gonzalez, Fabio Cavaliere, Nora Bengoa‐Vergniory, Amanda Sierra   +8 more
wiley   +1 more source

Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.

, 1992
Gregg L. Caporaso, Sam Gandy, Joseph D. Buxbaum, Paul Greengard   +3 more
openalex   +1 more source

Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats [PDF]

, 1995
WC Wallace, Ivan Lieberburg, Dale Schenk, Carmen Vigo‐Pelfrey, Keith L. Davis, Vahram Haroutunian   +5 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor

, 1990
LQ Luo, L Martin-Morris, K. Andrew White
openalex   +1 more source