Results 151 to 160 of about 252,333 (374)

Secretory cleavage site of Alzheimer amyloid precursor protein is heterogeneous in Down's syndrome brain [PDF]

, 1994
Fuyuki Kametania, Kikuko Tanaka, Takahiko Tokuda, Shu‐ichi Ikeda   +3 more
openalex   +1 more source

Recognition of the amyloid precursor protein by human γ-secretase

Science, 2019
R. Zhou, Guanghui Yang, Xuefei Guo, Qiang Zhou, J. Lei, Yigong Shi   +5 more
semanticscholar   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, EarlyView.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Exploring biomarkers of neurodegeneration in epilepsy: Critical insights

Epileptic Disorders, EarlyView.
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan, Syeda Amrah Hashmi, Jaideep Kapur, Anelyssa D'Abreu, Vineet Punia, Carol Manning, Vanessa L. Smith, Ifrah Zawar   +7 more
wiley   +1 more source

Processing of Alzheimer Aβ-Amyloid Precursor Protein: Cell Biology, Regulation, and Role in Alzheimer Disease

, 1994
Sam Gandy, Paul Greengard
openalex   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source

Influence of apolipoprotein E and its receptors on cere-bral amyloid precursor protein metabolism following

Chinese Journal of Traumatology, 2012
【Abstract】Traumatic brain injury (TBI) is the lead-ing cause of mortality and disability among young indi-viduals in our society, and globally the incidence of TBI is rising sharply. Mounting evidence has indicated that apolipoprotein E (apoE: protein;
ZHOU Shuai, SUN Xiao-chuan
doaj  

Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site.

, 1994
Gopal Thinakaran, Sangram S. Sisodia
openalex   +1 more source

Design Principles Of Inorganic‐Protein Hybrid Materials for Biomedicine

Exploration, EarlyView.
Inorganic protein hybrid materials (IPHMs) due to editable structure present unrivalled potential at the intersection of synthetic biology and materials science. The synthesis of IPHMs with a high degree of biosafety from bioactive units represents a shift in material design and synthesis.
Hao Liu, Xiaohui Liu, Hui Jiang, Xuemei Wang   +3 more
wiley   +1 more source

New Aspects of Analyzing Amyloid Fibrils [PDF]

arXiv
This is a summary of mathematical tools we used in research of analyzing the structure of proteins with amyloid form \cite{xi2024Top}. We defined several geometry indicators on the discrete curve namely the hop distance, the discrete curvature and the discrete torsion.
arxiv