Results 171 to 180 of about 82,488 (290)

EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder

Movement Disorders, EarlyView.
ABSTRACT Background Congenital mirror movement disorders (CMMs) are clinically and genetically heterogeneous in human patients. CMMs have not been documented to occur spontaneously in animals. Objective The objective of this work was to document the first case of CMMs spontaneously occurring in Weimaraner dogs and to identify the underlying genetic ...
Cleo Schwarz, Florian Bartenschlager, Olivia Kershaw, Judith Braun, Julien Guevar, Vidhya Jagannathan, Jörg T. Epplen, Wencke Reineking, Wolfgang Baumgärtner, Kailash P. Bhatia, Achim D. Gruber, Tosso Leeb   +11 more
wiley   +1 more source

Levels and Alternative Splicing of Amyloid β Protein Precursor (APP) Transcripts in Brains of APP Transgenic Mice and Humans with Alzheimer's Disease

, 1995
Edward Rockenstein, Lisa McConlogue, Hua Tan, Mike Power, Eliezer Masliah, Lennart Mucke   +5 more
openalex   +1 more source

TheDrosophilaβ-Amyloid Precursor Protein Homolog Promotes Synapse Differentiation at the Neuromuscular Junction [PDF]

, 1999
Laura Torroja, Mary Packard, Michael Gorczyca, K. Andrew White, Vivian Budnik   +4 more
openalex   +1 more source

Developmental deletion of amyloid precursor protein precludes transcriptional and proteomic responses to brain injury. [PDF]

Alzheimers Dement
Lacovich V, Čarna M, Novotný SJ, Wang S, Texlová K, Kovačovicova KL, Dragišić N, Havas D, Head BP, Geda YE, Limbäck-Stokin C, Stokin GB.   +11 more
europepmc   +1 more source

Amyloid precursor protein and its interacting proteins in neurodevelopment. [PDF]

Biochem Soc Trans, 2023
Chau DD, Ng LL, Zhai Y, Lau KF.
europepmc   +1 more source

Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1 [PDF]

, 1999
Ramin Homayouni, Dennis S. Rice, Michael Sheldon, Tom Curran   +3 more
openalex   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Neuron-Astrocyte Interactions in Aging and Alzheimer's Disease: Dysregulation of Amyloid Precursor Protein. [PDF]

Ageing Longev
Jáuregui GV, Parpura V.
europepmc   +1 more source

Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport

, 1999
Laura Torroja, Hsin Chu, Irina Kotovsky, K. Andrew White   +3 more
openalex   +1 more source

Alternative, Non-secretase Processing of Alzheimer's β-Amyloid Precursor Protein during Apoptosis by Caspase-6 and -8 [PDF]

, 1999
Luca Pellegrini, Brent J. Passer, Massimo Tabaton, J. Kelly Ganjei, Luciano D'adamio   +4 more
openalex   +1 more source